1. Corticosteroids, ACTH: electrolyte depletion, particularly hypokalaemia, may be increased

2. ACTH, thromboxane A2, blood pressure, heart rate, prostaglandins, U46619.

3. The release of ACTH-like immunoactivity (ACTH-LI) from perifused dispersed adenohypophyseal cells was examined under basal conditions and in response to various secretagogues.

4. These alterations are independent of the type of ACTH used.

5. Pigmentation, plasma ACTH, and sellar X-rays were assessed at intervals.

6. Addition of ACTH to the perfusate led to rapid decomposition of organella.

7. These results could also be confirmed by using the ACTH-infusion technic.

8. In the majority of cases, Cyclic CS is caused by an ACTH-secreting pituitary adenoma, but it can also be due to ectopic ACTH production or an adrenal adenoma …

9. A simple method is described to extract a representative part of the ACTH from plasma utilizing the high capacity of silicates (QUSO G-32) to adsorb free, intact ACTH.

10. The adrenocorticotrophic hormone (ACTH) stimulation test was assessed in red deer (Cervus elaphus).

11. Key words: natural killer cell activity (NKCA), adrenocorticotrophic hormone (ACTH), cortisol, rowing.

12. In the preferred embodiment, the ACTH polymeric microspheres are made using very cold temperatures to freeze the polymer-ACTH mixtures into polymeric microspheres with very high retention of biological activity and material.

13. Corticotropic (ACTH) cells did not appear cytologically different in freshwater and seawater fish.

14. Effects of ACTH and of cortisone upon Amputational wound healing processes in mice digits

15. Under none of the hormonal states did ANF suppress adrenocorticotropic hormone (ACTH) stimulated corticosterone secretion.

16. There were no precipitation lines between AFHS and the polypeptides ACTH, STH and α-MSH.

17. The interaction of AVONEX with corticosteroids or adrenocorticotropic hormone (ACTH) has not been studied systematically

18. The interaction of Rebif with corticosteroids or adrenocorticotropic hormone (ACTH) has not been studied systematically

19. The clinical studies indicate that MS patients can receive AVONEX and corticosteroids or ACTH during relapses

20. Livetrapped voles were subjected to behavioral tests, killed, and their isolated adrenals superfused and stimulated with ACTH.

21. Stimulation of amygdaloid nuclear complex resulted in a similar elevation of 17-OHCS and ACTH content.

22. Physostigmine mobilizes the corticosterone of the adrenal cortex in rat in the same way as ACTH.

23. The present invention relates to a molecule which can bind to adrenocorticotropic hormone (ACTH) with a high affinity.

24. We noted reduced plasma cortisol levels, i.e. insufficiency of the renal cortex, almost without exception in 32 children treated with corticosteroids in addition to ACTH, although initially depressed levels rose to normal values during ACTH medication in this group also.

25. For instance methods for the oral treatment of multiple sclerosis with alpha-MSH and ACTH are described.

26. Especially ulcerogenic in comparable dosage have been Triamcinolone, DOCA, Prednisone and Cortisone, less ulcerogenic Dexamethasone, Methylprednisolone and ACTH.

27. “There is a burst of pituitary ACTH activity at about 3 A.M., reaching a peak around 6 A.M.

28. Cyclic Cushing's syndrome (CS) involves rhythmic fluctuations in ACTH secretion resulting in a Cyclic variation of adrenal steroid production

29. On the other hand, a significant increase in triglycerides was noted in adrenal gland after 10 days of ACTH injections.

30. Catecholamines are then released into the blood stream usually when adrenocorticotropic hormone (ACTH) increases and cortisol levels are elevated

31. Androstenedione is secreted predominately by the adrenal gland and production is at least partly controlled by adrenocorticotropic hormone (ACTH)

32. Androstenedione is secreted predominately by the adrenal gland and production is at least partly controlled by adrenocorticotropic hormone (ACTH)

33. The ACTH response decreased at day 135–140, perhaps reflecting negative feedback control by the rising basalcortisol concentrations; (iii) adrenal responsiveness increases progressively between days 110–115 and 135–140 of gestation, as reflected by changes in the plasmacortisol concentration in response to endogenously released ACTH.

34. By impletation of an adrenocorticotropic hormone (ACTH) test homocygote and heterocygote carriers can be identified as well as unaffected women.

35. Cortisol secretion is regulated by the hypothalamic hormone, CRH, and the pituitary hormone, ACTH, in the hypothalamus-pituitary-adrenal axis

36. The serum levels of adrenocorticotrophic hormone (ACTH), 17 alpha-hydroxyprogesterone (17-alpha-OHP), testosterone, and aldosterone were found to be elevated.

37. In Whipple's disease in addition to the stromal alternations the surface epithelium also undergoes change during treatment with antibiotics, ACTH, and sulfapyridine.

38. Aldosterone responses to posture, ACTH, or angiotensin II did not correlate with associated changes in plasma cortisol, sodium, or potassium levels.

39. In contrast, the immunoreactions to anti-hGH, anti-hPRL, anti-ACTH, anti-MSH, anti-LPH and anti-endorphin sera were completely negative.

40. In this paper we communicate the very rare picture of a adrenocorticotropic (ACTH)-producing pheochromocytoma, giving rise to both clinical entities simultaneously.

41. However, the specific increase of adrenal androgen secretions during development without any detectable change in ACTH stimulation, the dissociation between adrenarche and gonadarche in several conditions, have led to postulate that the biochemical differentiation of the zona reticularis may require the action of an «adrenal factor» in addition to ACTH.

42. 9 In addition to pituitary gland, adrenocorticotropic hormone(ACTH)was also found to exist in the neurons of the central nervous system(CNS).

43. A hybrid gene consisting of CYP11B1 and CYP11B2 that produces aldosterone in an ACTH dependant manner can be found in FH type I.

44. In this context, the endocrine stress response is mainly represented by adrenaline (A), noradrenaline (NA), antidiuretic hormone/vasopressin (ADH), adrenocorticotropic hormone (ACTH), and cortisol.

45. An adrenocorticotropic hormone (ACTH) challenge was performed and serial blood and fecal (cecal and rectal) samples were collected and analyzed by a corticosterone RIA.

46. Your hypothalamus, common to all vertebrates, triggers your pituitary gland to secrete the hormone ACTH, making your adrenal gland shoot adrenaline into your blood.

47. In intact female rats, pretreatment with crystalline ACTH for at least 4 days reduces zoxazolamine paralysis and diminishes the toxicity of aniline, N-methylaniline, and acetanilide.

48. Electron microscopical investigations of the adrenal cortex of Rana temporaria L. after stimulation with ACTH have shown that amitotic cell divisions occur in this organ.

49. But some studies have also found that emotional tears contain higher levels of stress hormones, such as ACTH and enkephalin, an endorphin and natural pain killer.

50. Plasma concentrations of antidiuretic hormone (ADH), adrenocorticotropic hormone (ACTH), epinephrine, norepinephrine, aldosterone, plasma renin activity, Cortisol, and insulin were measured simultaneously during and following endotoxic hypotension.

51. In collaboration with various co-workers, he isolated several protein hormones, including adrenocorticotropic hormone (ACTH), which stimulates the adrenal cortex to increase its secretion of corticoids.

52. Due to the lack of clinical experience in multiple sclerosis patients, the use of Betaferon together with immunomodulators other than corticosteroids or ACTH is not recommended

53. In contrast, when related to basal levels aldosterone responsiveness to ACTH or angiotensin II appeared to be comparable in normal subjects and patients with renal disease.

54. The failure of tonin to stimulate aldosterone in hypophysectomized animals indicates a role of a pituitary hormone (probably ACTH) in the effect of tonin on adrenal secretion.

55. The stess of operation resulted in a transient increase in adenohypophyseal nucleic acid content, whereas the increase in secretion of ACTH induced by feedback control did not.

56. Six secretory cell types (prolactin-, ACTH-, somatotropin- (STH-), TSH-, and two presumptive gonadotropin- (GTH-) secreting cells) were identified in light or electron microscope preparations of goldfish pars distalis.

57. Indeed, the rapid fall of plasma ACTH concentrations in the early minutes following either the injections or the stop of the infusion is followed by a much slower phase.

58. [ACTH and anaphylaxis in guinea pigs; study of anaphylactic histaminic and Acetylcholinic asthma, of shock induced by peritoneal route and of reactivity in vitro of the smooth musculature]

59. These data suggest that the adrenal system of hypertensive patients produces less total corticoids; plasma ACTH levels of these patients therefore are higher than those of normal individuals.

60. The reduced ability of wild fish from contaminated sites to respond to a standardized ACTH challenge may be used as an early indicator of contamination-induced chronic stress.

61. Our investigations show that there is no conclusive evidence for adrenocortical insufficiency in patients with dystrophia myotonica as judged by the results of the intravenous modification of the ACTH test.

62. Increases in plasma concentrations of various glucose-raising hormones such as glucagon, catecholamines, adrenocorticotrophic hormone (ACTH), and cortisol are observed under certain conditions associated with stress (haemorrhage and hypoglycaemia).

63. In type 2 diabetic patients, the HPA axis is clearly hyperactive as evident in increased urinary free cortisol, diminished cortisol suppression after dexamethasone and increased ACTH-induced cortisol levels.

64. On the other hand, it is possible that the hyperplastic hilar cells adjust to the function of the cells of the adrenal cortex and their dependence on ACTH stimulation.

65. In 16 leucemic patients depot-ACTH did not increase (or increased less than in the controls) the renal excretion of dehydroepiandrosterone, etiocholanolone, androsterone and 11-OH-androsterone (androgen metabolites).

66. In contrast, both the effects of norepinephrine and ACTH were inhibited to about the same degree by the α-adrenolytic phenoxybenzamine and completely blocked by pretreatment with nicotinic acid.

67. As the reason for the impaired consciousness was suspected to be of neuroglucopenic origin a rapid adrenocorticotropic hormone (ACTH) stimulation test was first performed to rule out adrenal insufficiency.

68. The carboxyl groups of sheep adrenocorticotropic and beta-lipotropic hormones (ACTH and beta-LPH) were modified by glycine methyl ester and taurine using a water-soluble carbodiimide as a coupling agent.

69. The biological activity of the smaller molecular weight peptide (28 amino acid) was assessed by its inhibitory effect on 10−8 M ACTH-stimulated aldosterone secretion in rat zona glomeralosa cell suspension.

70. Plasma adrenaline, noradrenaline, ADH, ACTH, cortisol, and glucose as well as SAP and HR increased significantly (P<0.05) during the course of anaesthesia. The influence on lactate levels was not significant.

71. Gushing syndrome (CS) caused by ectopic adrenocorticotropic hormone (ACTH) production (EA) poses major challenges diagnostically by mimicking the pituitary-dependent form of CS and therapeutically by producing severe, life-threatening hypercortisolemia.

72. Of the various mechanisms, independently shown to play a role in the activation of the pituitary adrenocorticotrophic function, none proved essential to the release of ACTH under all conditions of stress.

73. Synthetic peptides corresponding to the amino acid sequences 1–5, 5–10 and 11–24 of natural ACTH with had no adrenocorticotropic actions were also without effect on lipolysis in vitro.

74. Provided herein are methods of treatment of acute respiratory distress syndrome comprising administration of adrenocorticotropic hormone (ACTH), or fragment, analog, complex or aggregate thereof, or any combination thereof, to an individual in need thereof.

75. Unlike the β-adrenolytics, prostaglandin E1 (PGE) inhibited in vitro spontaneous lipolysis as well as lipolysis induced by norepinephrine, ACTH or alloxan diabetes. PGE had no inhibitory effect in fat pads of fasting rats.

76. The basal and dynamic hormonal assessment indicated an ACTH-dependent hyperadrenocorticism, although the computed tomography of the sella turcica, performed in all the patients, was negative in 3 patients and doubtful in 2.

77. Indeed, the onset of adrenarche and gonadarche are dissociated in a variety of disorders of sexual maturation Adrenal androgen secretions are under the control of ACTH, as shown by a series of observations.

78. In humans, Study A6181004 revealed blunting of cortisol level response to adrenocorticotropic hormone (ACTH) stimulation testing in 13 patients receiving Sutent, although no adrenal gland structural changes were noted on CT/MRI studies.

79. Binding–sequestration of [125I][Phe2,Nle4]ACTH 1–24 exhibited brain regional differences in site densities with the following rank order: cortex > hypothalamus > hippocampus > striatum > cerebellum > midbrain > brainstem.

80. The action of desoxycorticosterone-acetate (DOCA), hydrocortisone (cortisol) and adrenocorticotrophic hormone (ACTH), upon the nitrogen and water-electrolyte excretion in some fishes (Gobius cephalarges, G. melanostomum and Trachurus mediterraneus) from the Black Sea was followed.