tolbutamide in English

noun
1
a synthetic compound used to lower blood sugar levels in the treatment of diabetes.
For example, sulfonamides used for infection were noted to lower blood sugar and led to drugs such as tolbutamide for diabetes.

Use "tolbutamide" in a sentence

Below are sample sentences containing the word "tolbutamide" from the English Dictionary. We can refer to these sentence patterns for sentences in case of finding sample sentences with the word "tolbutamide", or refer to the context using the word "tolbutamide" in the English Dictionary.

1. In the presence of tolbutamide liver slices from fasting rats formed less acetoacetic acid and β-hydroxybutyric acid.

2. In eleven patients with diabetes insipidus centralis the effect of chlorpropamide, tolbutamide, glybenclamide, glycodiazin, hydrochlorothiazide and vasopressin was investigated.

3. Females ranged from 0.6–15.0 mμg/ml (mean 5.1 mμg/ml) and 15 acromegalics from 8.0–103.0mμg/ml (mean 31.2 mμg/ml). — During a rapid tolbutamide tolerance test, serum HGH rose between 2.5- and 82-fold over the fasting levels within 10 to 70 minutes following the glucose nadir.

4. Although specific interaction studies were not conducted for all medicinal products, population pharmacokinetic analysis showed no effect of concomitant medication on sildenafil pharmacokinetics when grouped as CYP#C# inhibitors (such as tolbutamide, warfarin, phenytoin), CYP#D# inhibitors (such as selective serotonin reuptake inhibitors, tricyclic antidepressants), thiazide and related diuretics, loop and potassium sparing diuretics, angiotensin converting enzyme inhibitors, calcium channel blockers, beta-adrenoreceptor antagonists or inducers of CYP# metabolism (such as rifampicin, barbiturates