Use "synaptic" in a sentence

1. Cask -synaptic scaffolder calmodulin-associated serin/threonin kinase

2. Acetylcholinesterase: An enzyme that breaks down the neurotransmitter acetylcholine at the synaptic cleft (the space between two nerve cells) so the next nerve impulse can be transmitted across the synaptic gap

3. 5 Memory retention-the synaptic stability versus plasticity dilemma Wickliffe C.

4. Anticonvulsant action may be due to increase in synaptic GABA concentration

5. Acute anterior phenyl discord, being an indicator of synaptic receptor obstruction.

6. Animals harboring mutations in genes that affect synaptic transmission generally exhibit a change in their sensitivity to Aldicarb (either increased sensitivity for enhancements in synaptic transmission or decreased

7. Acetylcholinesterase (AChE) is a crucial enzyme in the cholinergic nerve system that hydrolyzes acetylcholine (ACh) and terminates synaptic signals by reducing the effective concentration of ACh in the synaptic clefts

8. It becomes part of their synaptic network, adding to nanites received previously

9. Another thing is, normally, acetylcholine is degraded in the synaptic cleft by Acetylcholinesterases

10. Astrocytes have many cytoplasmic processes that terminate on blood vessels, neuronal cell bodies, axons and synaptic terminals

11. " Regulates synaptic firing patterns... by running prolonged low-level voltage... through targeted areas of the brain. "

12. When a nerve experiences synaptic fatigue it becomes unable to stimulate the muscle that it innervates.

13. It represents changes of hundreds of millions, possibly billions of synaptic connections in your brain.

14. From the Cambridge English Corpus At their synaptic sites, photoreceptor terminals contain ribbons Apposed …

15. The neurotransmitters diffuse across the synaptic cleft and activate receptors on the postsynaptic neuron.

16. Synaptic formation strictly depends on cholesterol, produced and secreted by Astrocytes (that, most likely, provides a …

17. Results showed that alpha-synuclein blocked the synaptic plasticity associated with memory and motor function.

18. Multiple evidence points to malfunction of synapses (aberrant synaptic plasticity) as the reason behind epilepsy.

19. Axon terminal; synaptic Boutons are small swellings that are found at the terminal ends of axons

20. We use multidisciplinary approaches to understand mechanisms that orchestrate synaptic remodeling in the early postnatal period.

21. This transmission is made possible by the action of synaptic vesicles loaded with the neurotransmitters to be released.

22. Acetylcholinesterase is a type-B carboxylesterase enzyme located primarily in the synaptic cleft with a smaller concentration in the extrajunctional area

23. Aka synaptic Boutons, axon terminals are small swellings that are found at the terminal ends of axons

24. The hippocampus then encodes memories, probably by strengthening the synaptic connections stimulated during the original sensory experience.

25. Besides this mechanism a synaptic like, interaxonal irritation-transmission (Hering) by afferent and efferent fibres in this nervous plexus is supposed.

26. Synaptic plasticity, but not hippocampal neurogenesis, mediated the Counteractive effect of wolfberry on depression in rats(1) Cell Transplant

27. Gene-level associations in suicide Attempter families show overrepresentation of synaptic genes and genes differentially expressed in brain development.

28. Finally, stimulation of ventral roots elicits a synaptic potential that appears to be caused by glutamate released from afferent fibers in the ventral roots.

29. [Features of the Antidromal and synaptic activation of neurons of the Bekhterev nucleus reticularis tegmenti pontis induced by cortico- and cerebello-fugal spiking]

30. [Antidromal activation and synaptic processes of Deiters nucleus induced by stimulation of the inferior olive and reticular nucleus of the pontine tegmentum]

31. Special synaptic structures such as electron dense projections and accumulations of vesicles are situated predominantly in the angles of two neighbouring axons.

32. Thus, extensive Arborization can be considered a sign of complexity due to the increased number of synaptic connections it allows for

33. SYNAPSE TRANSMISSION scientists also studied synaptic computation at bipolar and amacrine cell terminals in the presence and absence of Müller cells.

34. 12 Selective adhesion mechanisms are known to be involved in nerve-muscle recognition and control of synaptic development in several vertebrate systems.

35. Mice fed a diet high in Canola oil displayed a reduction of postsynaptic density protein-95, which is an indicator of decreased synaptic integrity.

36. Synaptic Boutons are typically the sites where synapses with other neurons are found, and neurotransmitters are stored here to communicate with other neurons via these synapses

37. Acetylcholinesterases (AChEs) terminate transmission of neuronal impulses by rapid hydrolysis of acetylcholine (ACh), and are therefore primarily associated with synaptic contacts in nerves and muscle (Fig

38. Many Axons are commissural, crossing the midline to course in Axon tracts and innervate synaptic targets on the opposite side of the neuraxis

39. Pupillary responses are spared in a patient with Cortical blindness because they rely on synaptic reflexes through the brainstem and do not require Cortical inputs.

40. Using quantitative analyses on immunolabelled preparations, we have established that this morphological synaptic plasticity affects both inhibitory and excitatory afferent inputs to oxytocin neurons.

41. The increase in extracellular K+ activity depolarizes the membranes of neurones, glial cells, and primary afferent fibres and may eventually lead to either facilitation or inhibition of synaptic transmission.

42. Author summary To understand synaptic mechanisms underlying neuronal computations, a fundamental approach is to use voltage clamp to measure the dynamics of excitatory and inhibitory input Conductances

43. Julia Brasch's PubMed Literature Search Biological Chemistry Program Molecular Biology Program Synaptic organization, cell-cell adhesion, structural biology, electron cryo-tomography, cryo-EM, X-ray crystallography, Biophysics

44. In line with this, synaptic localization of mitochondria increased as Boutons aged and showed differing patterns of localization at en passant and terminaux Boutons

45. Social Anhedonia is seen in teenagers, maybe due to the development of neuronal and synaptic pruning of brain regions which is needed for significant

46. 27 We has discussed the mechanism of the trivalent synaptic adjustment, and it's important use to control the chiasmata and disjunction of the chromosomes.

47. NPY-IR amacrine cells predominantly received synaptic input from bipolar cell axon terminals (86%), while a few input from other amacrine cell processes (14%).

48. Anterograde (Orthograde) Axonal Transport is the mechanism whereby packets of chemicals and organelles are transported within the Axoplasm between the cell body and the synaptic boutons.

49. The bipolar-cell axons extend Afferently beyond the retina, leaving the eyeball to form the optic nerve, which enters the brain to make further synaptic connections

50. Anterograde (Orthograde) Axonal Transport is the mechanism whereby packets of chemicals and organelles are transported within the axoplasm between the cell body and the synaptic boutons

51. 23 Long-term potentiation (LTP) and long-term depression (LTD), two forms of synaptic plasticity, are believed to underlie the mechanism of learning and memory.

52. The bipolar-cell axons extend Afferently beyond the retina, leaving the eyeball to form the optic nerve, which enters the brain to make further synaptic connections.

53. The bipolar-cell axons extend Afferently beyond the retina, leaving the eyeball to form the optic nerve, which enters the brain to make further synaptic connections

54. The liberated choline is taken up again by the pre-synaptic neuron and ACh is synthesized by combining with acetyl-CoA through the action of choline acetyltransferase.

55. Electrophysiological experiments were performed in prepared brain slices to test the effect of endogenous and exogenous cannabinoids on synaptic transmission and long-term potentiation (LTP) in the amygdala.

56. Astrocytes are the most common glial cell type in the brain, and perform many functions such as neurotransmitter uptake and release, modulation of synaptic transmission, and nervous system repair

57. In the aganglionic, constricted section of the colon from two cases of Hirschsprung's disease, adrenergic and cholinergic axons establish frequent synaptic contacts with smooth muscle cells by exposed varicosities.

58. The extensive synaptic Arborizations are present only in DC neurons [anterior DC (aDC) and posterior DC (pDC) neurons] and not in the closely related SC mechanosensory neurons, although their target areas overlap almost perfectly (Fig

59. Taken together, these results suggest that endogenous CGRP and ATP co-released with ACh from the nerve terminal may promote synaptic development by potentiating postsynaptic ACh channel activity during the early phase of synaptogenesis.

60. In contrast, the newly developed KDS2010 Circumvents the issues of selegiline by significantly attenuating increased astrocytic GABA levels and astrogliosis, enhancing synaptic transmission, and rescuing learning and memory impairments in APP/PS1 …

61. Amitriptyline inhibits the re-uptake of norepinephrine and serotonin by the presynaptic neuronal membrane in the central nervous system (CNS), thereby increasing the synaptic concentration of norepinephrine and serotonin.Due to constant stimulation to these receptors, Amitriptyline may produce a

62. The normal recovery cycle of the H-reflex with paired stimuli demonstrated a balance of excitatory and inhibitory inputs at the spinal and supraspinal level; the posttetanic facilitation of H-amplitude shows a normal synaptic transmission of Ia-afferents.

63. Up to 10% cash back  · Antidromal and synaptic responses were demonstrated in the same parietal cortex neurons, demonstrating a double connection between the intrinsic nuclei of the pons and the associated parietal cortex

64. Astrocytes are the most numerous cell type within the central nervous system (CNS) and perform a variety of tasks, from axon guidance and synaptic support, to the control of the blood brain barrier and blood flow

65. Aches: Acetylcholinesterase (synaptic form, biochemistry) Aches: Advocacy Committee for Human Experimentation Survivors: Aches: Abdominal pain, Chest pain, HeadAches, Eye problems, Sweling and/or aching in the legs and thighs (mnemonic for side effects of the birth control pill)

66. Unlike sensory Cortices, transmodal Cortices have a less hierarchical organisation with dense interconnectivity and top-down projections that tend to jump synaptic levels and that allow spatially distributed areas to respond flexibly to different types of information [5–10].

67. ‘The correlation between changes in the kinetics of synaptic current and quantal Amplitude remains strong for the corrected values as well.’ ‘Practical researchers are only too aware, however, that the optical output can frequently vary significantly in Amplitude and spatial quality from point to …

68. An action potential propagates the electrical activity along the membrane of the neuron's dendrites to the cell body and then Afferently down the length of the axon to the axon terminal, where it triggers the release of neurotransmitters into the synaptic cleft.

69. The transmission of nociceptive stimuli in primary afferent neurons critically depends on a particular repertoire of various types of ion channels such as TRP channels and sodium and potassium channels, as well as calcium channels that either detect noxious stimuli, or regulate cellular excitability and synaptic transmission.

70. Capsaicin has been used: • to study its effects on chromatin remodeling and gene expression related to synaptic plasticity • to study TRPV1 channel signaling in H2C1 cells (which are human embryonic kidney 293 cells expressing TRPV1 channels) Packaging 1 g in glass bottle 250 mg in glass bottle

71. In mammalian Cochleae, the bulk of auditory information is transmitted to the brain via the inner hair cells, which provide the sole synaptic inputs to 90% to 95% of the afferent fibers of the auditory nerve ().Auditory nerve excitation is triggered by depolarization of inner hair cells upon deflection of their “hair” bundles toward the taller stereocilia (2, 3).

72. Axoplasm contains both the mRNA and ribonuclearprotein required for axonal protein synthesis.; In Axoplasmic transport, materials are carried through the Axoplasm to or from the soma.; Axoplasm is integral to the overall function of neurons in propagating action potential through the axon.; Furthermore, Axoplasm contains the pre-synaptic vesicles of neurotransmitter which are eventually

73. Crimpy promotes the function of neuron-derived Gbb in synaptic transmission Cmpy prevents neuronal Gbb from acting as a pro-growth signal (James and Broihier, 2011), raising the possibility that cmpy mutants exhibit increased pro-growth Gbb signaling at the expense of the normal function of neuronal Gbb in promoting glutamate release.

74. Axon terminals (also called synaptic Boutons, terminal Boutons, or end-feet) are distal terminations of the telodendria (branches) of an axon.An axon, also called a nerve fiber, is a long, slender projection of a nerve cell, or neuron, that conducts electrical impulses called action potentials away from the neuron's cell body, or soma, in order to transmit those impulses to other neurons

75. Apomorphine is a non-ergoline dopamine agonist with high in vitro binding affinity for the dopamine D4 receptor, and moderate affinity for the dopamine D2, D3, and D5, and adrenergic α1D, α2B, α2C receptors.The precise mechanism of action of Apomorphine as a treatment for Parkinson's disease is unknown, although it is believed to be due to stimulation of post-synaptic