1. 3 Mouse bone marrow polychromatic erythrocyte micronucleus test was negative.

2. Biphenyl tested negative in the (CD-1) mouse micronucleus test (Klimisch1 key study of Gollapudi et al., 2007)

3. 13 The antimutagenic effect of Cortex acanthopanasia Radicis(CAR) has been studied by mean of micronucleus test of mouse bone marrow polychromatic erythrocyte (PCE) and mouse spermatid malformation test.

4. By obtaining a significant change in the proportion of immature erythrocytes among total erythrocytes in the bone marrow, at the doses and sampling times used in the micronucleus test or by measuring a significant reduction in mitotic index for the chromosomal aberration assay. ii.