proteasome in English

noun
1
a protein complex in cells containing proteases; it breaks down proteins that have been tagged by ubiquitin.
In the context of the cell, the unfolding process participates in several important steps in cellular physiology, such as protein turnover in proteasomes .

Use "proteasome" in a sentence

Below are sample sentences containing the word "proteasome" from the English Dictionary. We can refer to these sentence patterns for sentences in case of finding sample sentences with the word "proteasome", or refer to the context using the word "proteasome" in the English Dictionary.

1. 19 Ubiquitin - proteasome pathway is a highly effective protein - degradation pathway in the eukaryotic cells.

2. Appraising the roles of CBLL1 and the ubiquitin/proteasome system for flavivirus entry and replication J Virol

3. Assays for compound screening to inhibit the proteasome and deubiquitinases are offered by Reaction Biology with fluorescent-based activity Assays

4. In another embodiment an injection catheter for delivery an anti-restenotic effective amount of proteasome inhibitor to the adventitia is provided.

5. Anaphase-promoting complex (also called the cyclosome or APC/C) is an E3 ubiquitin ligase that marks target cell cycle proteins for degradation by the 26S proteasome

6. Argyrins, a family of natural products, were identified as potential anti-cancer agents that directly inhibit proteasome activity, which is often aberrantly regulated in cancer.

7. In a particular embodiment, the invention provides a method for determining whether a subject with multiple myeloma is likely to respond to a treatment with a proteasome inhibitor wherein the method comprises the step of performing, on a sample from the subject, a gene expression analysis of a number of N genes selected from the group consisting of the genes NUAK1, ITGB7, AGMAT, TFAP2C, CCDC85A, CLEC7A, TMEM37, RNF144A, and CMPK2, wherein N is at least 2and wherein it is concluded that the subject is likely to respond to a treatment with a proteasome inhibitor in case that at least 2 of said N genes are aberrantly expressed.