1. 19 Ubiquitin - proteasome pathway is a highly effective protein - degradation pathway in the eukaryotic cells.

2. Appraising the roles of CBLL1 and the ubiquitin/proteasome system for flavivirus entry and replication J Virol

3. Assays for compound screening to inhibit the proteasome and deubiquitinases are offered by Reaction Biology with fluorescent-based activity Assays

4. In another embodiment an injection catheter for delivery an anti-restenotic effective amount of proteasome inhibitor to the adventitia is provided.

5. Anaphase-promoting complex (also called the cyclosome or APC/C) is an E3 ubiquitin ligase that marks target cell cycle proteins for degradation by the 26S proteasome

6. Argyrins, a family of natural products, were identified as potential anti-cancer agents that directly inhibit proteasome activity, which is often aberrantly regulated in cancer.

7. In a particular embodiment, the invention provides a method for determining whether a subject with multiple myeloma is likely to respond to a treatment with a proteasome inhibitor wherein the method comprises the step of performing, on a sample from the subject, a gene expression analysis of a number of N genes selected from the group consisting of the genes NUAK1, ITGB7, AGMAT, TFAP2C, CCDC85A, CLEC7A, TMEM37, RNF144A, and CMPK2, wherein N is at least 2and wherein it is concluded that the subject is likely to respond to a treatment with a proteasome inhibitor in case that at least 2 of said N genes are aberrantly expressed.