dcis in English

DCIS (ductal carcinoma in situ)

noninvasive malignant-looking abnormal cells inside the ducts of breast in wome

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1. We investigated the mechanisms of apoptosis in Comedo-DCIS and its role in conversion of Comedo-DCIS to invasive c …

2. Comedo type DCIS (also referred to as Comedocarcinoma) tends to be more aggressive than the non-Comedo types of DCIS

3. Non-Comedo DCIS encompasses all other subtypes and includes the following types:

4. Comedo-DCIS is a histologic subtype of preinvasive breast neoplasia that is characterized by prominent apoptotic cell death and has greater malignant potential than other DCIS subtypes

5. In Comedo, DCIS cells are large with pleomorphic nuclei and abnormal mitoses

6. Pathologists are able to easily distinguish between Comedo type DCIS and other non-Comedo types when examining the cells under a microscope because Comedo type DCIS tends to plug the center of the breast ducts with necrosis

7. Abbreviated breast MRI detected all 17 women with invasive cancer and 5 of 6 women with DCIS

8. DCIS is designated as Comedo if atypical cells with abundant luminal necrosis fill at least one duct

9. 28 However, in contract to papillary DCIS, myoepithelial cells are also absent in the periphery of the tumor nodule of EPC.

10. Comedocarcinomas are usually non-infiltrating and intraductal tumors, characterized as a Comedo -type, high- grade ductal carcinoma in situ (DCIS).

11. Pagetoid spread into adjacent ductolobular units was frequently seen in E-DCIS, and the expanded lobules were often not rimmed by myoepithelial cells.

12. 17 If pathologic diagnoses are DCIS, ADH, papilloma, ALH et al, we need to submit all segmental mastectomy or excional biopsy specimen for microscopic examination.

13. In situ breast cancer (ductal Carcinoma in situ or DCIS) is a cancer that starts in a milk duct and has not grown into the rest of the breast tissue

14. High-grade DCIS is sometimes described as "Comedo" or "Comedo necrosis." Comedo refers to areas of dead (necrotic) cancer cells, which build up inside the tumor

15. Abundant eosinophilic Apocrine cytoplasm; Same criteria as usual DCIS except that usual nuclear size criteria cannot be used as nuclei in Apocrine metaplasia are typically large; Special nuclear size criteria based on comparison to benign Apocrine metaplastic cells

16. Tests on lg-DCIS and FEA occurring in association with tubular breast carcinomas demonstrated a direct clonal relationship in 67 and 70% of cases, respectively, and comparative allelotyping revealed a high degree of homology in the patterns of chromosomal imbalances.

17. A Comedo-type ductal carcinoma in situ, also known as Comedocarcinoma in situ is the high grade subtype of ductal carcinoma in situ (DCIS). It completely fills and dilates the ducts and lobules in TDLU with plugs of high grade tumor cells with central necrosis "Comedonecrosis"

18. Apocrine metaplastic lesions have been shown to be androgen receptor (AR) positive and negative for oestrogen receptor (ER) and progesterone receptor (PR) expression.17,38–40 This unique receptor profile is largely retained in Apocrine DCIS,25,39 but is more variable in invasive Apocrine carcinomas39,41,42 (see Table 1).