1. XAnthine oxidase is important in the oxidation of hypoxantine to xAnthine and uric acid

2. There is a genetic disease of xAnthine metabolism, xanthinuria, due to deficiency of an enzyme, xAnthine dehydrogenase, needed to process xAnthine in the body

3. Chemically, xAnthine is a purine

4. XAnthine is produced naturally by both plants and animals

5. XAnthine is a type of purine, and xanthinuria is a genetic deficiency of xAnthine oxidase, a defect in purine metabolism

6. XAnthine oxidase (XO, sometimes ' XAO ') is a form of xAnthine oxidoreductase, a type of enzyme that generates reactive oxygen species

7. XAnthine oxidase (XO), also known as xAnthine oxidoreductase, has long been considered an important host defense molecule in the intestine and in breastfed infants

8. Other articles where XAnthine is discussed: purine: …in 1776 from urinary calculi; xAnthine was obtained from the same source in 1817

9. It is a tautomer of a 7H-xAnthine

10. Allopurinol is a xanthine oxidase inhibitor that works by

11. See the full definition of xAnthine at merriam-webster.com » 102 Playable Words can be made from "XAnthine" 2-Letter Words ( 21 found )

12. XAnthine oxidase activity increases in liver and plasma of diabetic rats

13. Two inherited forms of xanthinuria principally result from a deficiency of the enzyme xAnthine dehydrogenase, which is the enzyme responsible for degrading hypoxAnthine and xAnthine to uric acid.

14. XAnthine also occurs in tea, as does caffeine, another purine compound

15. Structure, properties, spectra, suppliers and links for: XAnthine, 69-89-6.

16. The metabolites for ara-G were xanthine, uric acid, and allantoin.

17. XAnthine oxidase is an important source of free radicals in vivo

18. Aldehyde oxidase (AO) belongs to the same family of xanthine oxidoreductases as XO

19. Zyloprim (Allopurinol) is a xanthine oxidase inhibitor that reduces the production of uric acid

20. Xanthinuria is a descriptive term for excess urinary excretion of the purine base xAnthine

21. XAnthine oxidase converts into uric acid causing gout, a painful inflammatory condition

22. These enzymes catalyze the oxidation of hypoxAnthine to xAnthine and can further catalyze the oxidation of xAnthine to uric acid.These enzymes play an important role in the catabolism of purines in some species, including humans.

23. 3 Unlike caffeine, these molecules have only two methyl groups attached to their xanthine skeleton.

24. XAnthine (3,7-dihydro-purine-2,6-dione) is a product on the pathway of purine degradation, subsequently converted to uric acid by the action of the xAnthine oxidase enzyme (Voet et al., 2008)

25. Examples of how to use “xAnthine” in a sentence from the Cambridge Dictionary Labs

26. Gout - an overview The effects of these extracts on the metabolic conversion of xAnthine …

27. xAnthine (Xa) and then, in a second oxidation step, Xa to uric acid (Ua), as shown in Fig

28. XAnthine is produced when certain types of proteins are broken down within the body; while most cats further breakdown xAnthine to other substances that are more easily excreted, some pets are deficient in an enzyme that is required for this breakdown to occur.

29. XAnthine: A substance found in caffeine, theobromine, and theophylline and encountered in tea, coffee, and the colas

30. (Elements & Compounds) any substituted derivative of xAnthine, esp one of the three pharmacologically active methylated xAnthines

31. Xanthine oxidase was immobilized by adsorption on control pore SiO2 or TiO2 beads in glass tube columns.

32. The activity of xanthine oxidase is directly proportional to the amount of molybdenum in the body.

33. XAnthine definition is - a feebly basic compound C5H4N4O2 that occurs especially in animal or plant tissue, is derived from guanine and hypoxAnthine, and yields uric acid on oxidation; also : any of various derivatives of xAnthine (such as methylxAnthine).

34. XAnthine is a purine base found in most human body tissues and fluids as well as in other organisms

35. This bypass of the hypoxAnthine salvage pathway may explain why xAnthine is the predominant urinary purine excreted in xanthinuria.

36. XAnthine bladder stones are an uncommon type of urinary stone that can occur in both dogs and cats

37. XAnthine is a purine base found in most human body tissues and fluids and in other organisms.

38. Allopurinol, a xanthine oxidase inhibitor used in the prevention of recurrent gout, should rarely be used to treat angina

39. XAnthine, also known as 1H-Purine-2,6-dione, is a purine base found in human body fluids and tissues

40. XAnthine is a purine base found in most human body tissues and fluids as well as in other organisms

41. XAnthine bladder stones are an uncommon type of urinary stone that can occur in both dogs and cats

42. XAnthine is found in coffee, tea and cola drinks as well as substances like caffeine, theobromine and theophylline

43. XAnthine is produced when certain types of proteins are broken down within the body; while most dogs further breakdown xAnthine to other substances that are more easily excreted, some pets are deficient in an enzyme that is required for this breakdown to occur.

44. Allopurinol is used for treating gout caused by excessive levels of uric acid in the blood (hyperuricemia).It is a xanthine oxidase inhibitor and is similar to febuxostat ().Uric acid is a by product from the breakdown of certain proteins (purines) in the body by enzymes called xanthine oxidases.

45. XAnthine stones (purine stones) are seen in patients with severe hyperuricemia taking allopurinol, or in those with rare inherited forms of xanthinuria

46. Caffeine contains a chemical called xAnthine, which has been shown to stimulate tear production when applied topically to the eye

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49. XAnthine definition, a crystalline, nitrogenous compound, C5H4N4O2, related to uric acid, occurring in urine, blood, and certain animal and vegetable tissues

50. What does xAnthine mean? A white, crystalline, nitrogenous compound, C5H4N4O2, resembling uric acid: it is present in blood, urine, and certain p

51. 55,65 AO can effectively hydroxylate most Aldehydes to carboxylic acid but is unreactive toward xanthine; its oxidative and reductive half-reactions of AO do

52. ‘XAnthine oxidase catalyses the oxidation of xAnthine and hypoxAnthine to uric acid and is a well-known producer of superoxide radicals.’ More example sentences ‘It appears that the purine metabolic system in humans has found a way to avoid the overproduction of uric acid by downregulating the Xor gene expression, the product converting

53. 9H-xAnthine is an oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated

54. Purpurogallin scavenges not only xanthine oxidase generated oxyradicals, but also non-enzymatically produced peroxyl radicals, more actively than equimolar levels of Trolox or allopurinol.

55. As yet, there is insufficient published research to confirm that ingesting xAnthine provides the same tear-producing effect, though preliminary studies seem to suggest that it does.

56. (1987) presented data indicating that xAnthine is mainly derived from GTP to GMP degradation in hereditary xanthinuria both in the basal state and after intravenous fructose

57. It is characterized by high levels of a compound called xAnthine and very low levels of another compound called uric acid in the blood and urine.

58. XAnthine Market report is aiming at providing a thorough insight into the top to bottom analysis of the market growth, manufacturers, opportunities &future forecast (2021- 2027)

59. xAnthine ( plural xAnthines ) ( chemistry) Any of a group of alkaloids that include caffeine, theophylline, and theobromine as well as the parent compound, a precursor of uric acid found in …

60. Introduction Xanthinuria type I, a rare hereditary disorder, is characterized by a marked and isolated defi-ciency of xAnthine oxidase activity in the ti-ssues, resulting in hypouricemia and hypourico-suria.

61. xAnthine: 1 n crystalline oxidation product of the metabolism of nucleoproteins; precursor of uric acid; found in many organs and in urine Type of: organic compound any compound of carbon and another element or a radical

62. Computationally exploring novel xanthine oxidase inhibitors using docking-based 3D-QSAR, molecular dynamics, and virtual screening† Yanming Chen , a Ya Gao , a Fengshou Wu , a Xiaogang Luo , ab Xiulian Ju a and Genyan Liu * a

63. Preferred compounds capable of reducing the uric acid level are selected from the group consisting of xanthine oxidase inhibitors, such as allopurinol, recombinant enzyme uricase and uricosuric compound capable of enhancing uric acid excretion, such as probenecid.

64. IL-10 Leukocyte left ventricular immune neural liver abscess patients mitral casepatients platelet case-patients ±10.2 psoas abscess xAnthine derivatives IL-12 lung patient β-blockers cardiac prostaglandin ±0.5 β-agonists chickenpox tricuspid calcium channel blockers ±12.5 heart Patients hemoglobin blood pyrogens IL-8 upper respiratory

65. Additionally, low doses of DEX also resulted in increases in hepatic UA concentration and urinary UA excretion, which were associated with an induction of xAnthine oxidoreductase (XOR) in the liver and a downregulation of urate transporter 1 (URAT1) in the kidney, respectively

66. xAnthine[′zan‚thēn] (organic chemistry) C5H4N4O2 A toxic yellow-white purine base that is found in blood and urine, and occasionally in plants; it is a powder, insoluble in water and acids, soluble in caustic soda; sublimes when heated; used in medicine and as a chemical intermediate

67. Allopurinol is a structural isomer of hypoxanthine.Allopurinol inhibits xanthine oxidase, an enzyme that converts oxypurines to uric acid.By blocking the production of uric acid, this agent decreases serum and urine concentrations of uric acid, thereby providing protection against uric acid-mediated end organ damage in conditions associated with excessive production of uric acid, i.e