1. Metoprolol did not alter the pharmacokinetic profile of venlafaxine or its active metabolite, O-desmethylvenlafaxine

2. Warning, however, that Venlafaxine can give serious abstinence symptoms for several months when you quit using it.

3.   Effexor (venlafaxine), Wellbutrin (bupropion), and Prozac (fluoxetine) are Antidepressants that are not as likely to cause weight gain, and many people even

4. The use of venlafaxine has been associated with the development of akathisia, characterised by a subjectively unpleasant or distressing restlessness and need to move often accompanied by an inability to sit or stand still

5. The invention involves the combined administration of an antagonist of the NMDA receptor and an antidepressant, for example a combination of amantadine and citalopram or venlafaxine, or an antagonist of the NMDA receptor and an anxiolytic agent, for example amantadine and buspirone or trazodone, in order to improve unwanted tremors, akinesia, dyskinesia or bradykinesia associated with one or more different disorders or diseases.