1. The anti-trombogenic coating being presented in a thermodynamic non-equilibrium labile state defined by a surface energy favorable for immobilizing of albumen thereon while preventing adhesion of thrombogenic proteins thereto.

2. We describe four cases of acardius (one of hemiacardius, two of holoacardius acephalus, and one of holacardius amorphus) and present the current range of therapeutic possibilities: control of amniotic fluid by repeated amniocentesis or indomethacin therapy, administration of digoxin to the mother, selective preterm delivery of the acardiac twin by hysterotomy, interruption of the anastomoses by injection of thrombogenic coils, sclerosing agents, umbilical cord ligation, fetoscopic laser coagulation, and thermocoagulation.