1. Bradykinin, an inflammatory mediator, sensitizes nociceptor peripheral terminals reducing pain threshold

2. It sensitizes the intestine to further doses of Angiotonin and alters the intestine such that renin-activator contracts it

3. Here, we demonstrate that by hydrolyzing 15-HpETE-PE, iPLA 2 β Averts ferroptosis, whereas its genetic or pharmacological inactivation sensitizes cells to ferroptosis.

4. Chronic estrogen sensitizes uterine cervical Afferents to mechanical distension, but whether this reflects changes in afferent neurotransmitter or excitatory ion channel expression is unknown.

5. It sensitizes the intestine to further doses of Angiotonin and alters the intestine such that renin-activator contracts it. Angiotonin also constricts the vessels of a rabbit's ear perfused with blood or Ringer's solution.