1. Dreaming occurs especially during periods of rapid eye movement, called REM sleep.

2. 21 Rapid eye movement sleep deprivation can modulate visceral hypersensitivity by increasing pain threshold to CRD.

3. Active sleep, or REM (Rapid Eye Movement) sleep, takes up about 25 percent of our total sleeping time.

4. Positron emission tomography was used to measure cerebral activity and to evaluate regional interrelationships within visual Cortices and their projections during rapid eye movement (REM) sleep in human subjects

5. Complex feedback loops involving cytokines, such as interleukin-1 and tumor necrosis factor-α produced in response to infection, appear to also play a role in the regulation of non-rapid eye movement (REM) sleep.