1. Methods 78 patients were sinus rhythm by oral quinidine or amiodarone or direct current cardioversion.

2. Cinchonism refers to a syndrome caused by any of the cinchona alkaloids, including quinidine

3. Cinchonism is a pathological condition caused by an overdose of cinchona bark or its alkaloids quinine and quinidine

4. Cinchonism is most often a sign of chronic quinidine toxicity, but it may appear in sensitive patients after a single moderate dose

5. Cinchonism occurs from quinidine or quinine use (a class I antiarrhythmic drug) and consists of tinnitus, blurred vision, dizziness, nausea and vomiting

6. See Table 4 Frequent: vomiting, cramps, cinchonism (tinnitus, nausea, headache, blurred vision) Occasional: widening of QRS complex, cardiac disturbance, fever, delirium, rashesRare: acute hemolytic anemia quinidine sulphate

7. See Table 4 Frequent: nausea, vomiting, cramps, cinchonism Occasional: widening of QRS complex, cardiac disturbance, headache, fever, delirium, rashes Rare: acute hemolytic anemia 10. quinidine sulphate - 200 mg Prevention: no indication Treatment:

8. Eleven indole-alkaloids from Tabernanthe Iboga Baillon, Conopharyngia durissima Stapf and Voacanga africana Stapf (Apocynaceae), harmane and harmine, two synthetic azepinoindoles, quinidine and quindonium produced in anaesthetized guinea-pigs a bradycardia which was resistant against vagotomy and atropine.

9. other conditions, e. g. rheumathoid arthritis or atopic dermatitis) or verapamil (a medicine used to lower blood pressure, to correct hearth rhythm or to treat angina pectoris) or quinidine (a medicine used to correct heart rhythm