1. 25 Undifferentiated carcinomas with osteoclastic - like giant cells carry a similar prognosis to ductal adenocarcinoma.

2. Calcitonin is a powerful inhibitor of osteoclastic activity (the cells which continuously reabsorb bone)

3. Conclusion The sensitized T lymphocytes could promote osteoclastic differentiation and the ability of bone resorption.

4. Conclusion:Nylestriol can inhibit expression of IL 6 mRNA, reduce osteoclastic bone resorption and decrease loss of bone mass.

5. In contrast to the regional accelerated phenomenon,3, 4 this was a systemic Acceleratory phenomenon in which surgery of the bone induced, not only a regional, but also a systemic and transient increase in osteoclastic activity and osteoporosity