1. The olfactory bulbs of the olfactory nerve lie on either side of the crista galli on top of the cribriform plate.

2. Naegleria fowleri propagates in warm, stagnant bodies of freshwater (typically during the summer months), and enters the central nervous system after insufflation of infected water by attaching itself to the olfactory nerve.

3. Anosmia occurs when intranasal swelling or other obstruction prevents odors from gaining access to the olfactory area; when the olfactory neuroepithelium is destroyed; or when the olfactory nerve fila, bulbs, tracts, or central connections are destroyed (see table Some Causes of Anosmia).