1. Nucleoside Analogue a structural

2. Nucleoside Analogue a structural

3. Azt is a nucleoside reverse transcriptase inhibitor

4. Tion, naturally-oc curring Bacteric idal nucleoside

5. Nucleoside transport in humans is mediated by members of two unrelated protein families, the SLC28 family of cation-linked Concentrative nucleoside transporters (CNTs) and the SLC29 family of energy-independent, equilibrative nucleoside transporters (ENTs).

6. Adenine combined with ribose produces the nucleoside adenosine

7. Azt is a nucleoside analog reverse-transcriptase inhibitor

8. Concentrative nucleoside transporters (CNTs), members of the solute carrier (SLC) 28 transporter family, facilitate the salvage of nucleosides and therapeutic nucleoside derivatives across the plasma membrane

9. Adenosine triphosphate (Atp) is chemically classified as a nucleoside triphosphate

10. Method for preparing acyclic nucleoside monophosphate compound as antiviral drug

11. Concentrative nucleoside transporters (CNTs) mediate the salvage of nucleosides and the transport of therapeutic nucleoside analogues across plasma membranes by coupling the transport of ligands to the sodium gradient

12. Adenosine is an endogenous nucleoside occurring in all cells of the body

13. The present invention relates to polymeric conjugates of adenine nucleoside analogs.

14. Azt is a type of anti-HIV drug called a nucleoside analogue (“nuke”)

15. Adenosine is a short acting endogenous molecule that is a purine nucleoside

16. Acyclovir Sodium Injection is a synthetic nucleoside analog, active against herpes viruses

17. Adenosine definition, a white, crystalline, water-soluble nucleoside, C10H13N5O4, of adenine and ribose

18. ZOVIRAX is the brand name for Acyclovir, a synthetic nucleoside analog active against herpesviruses

19. Thymine combined with deoxyribose creates the nucleoside deoxythymidine, which is synonymous with the term thymidine.

20. Disclosed are polymeric compounds which are useful as prodrugs, comprising a chain of monomeric nucleosides, nucleoside analogs or abasic nucleosides, wherein at least one of the nucleosides or nucleoside analogs or a heterocyclic derivative thereof is pharmaceutically active and the nucleosides, nucleoside analogs or abasic nucleosides are linked by a phosphodiester group, a phosphorothioate group or an H-, alkyl or alkenyl phosphonate group.

21. Acyclovir: ValAcyclovir • Zovirax® • Valtrex® Drug class • Antiviral, Synthetic nucleoside analogue: Chemical structure • Structurally, valAcyclovir differs from Acyclovir by the presence of the amino acid valine attached to the 5-hydroxyl group of the nucleoside

22. The 1H nmr spectroscopic properties of an acyclic nucleoside analog derived from uridine are also described.

23. Adenosine is a naturally occurring purine nucleoside that forms from the breakdown of Adenosine triphosphate (ATP)

24. Concentrative nucleoside transporter 1 (CNT1) is a protein that in humans is encoded by the SLC28A1 gene.

25. Adenosine (plural Adenosines) (biochemistry, genetics, organic chemistry) A nucleoside derived from adenine and ribose, found in striated muscle tissue

26. Azidothymidine (AZT, also called Zidovudine) is a nucleoside analog reverse-transcriptase inhibitor useful against the HIV virus

27. Concentrative and Equilibrative Nucleoside Transporter proteins (CNT and ENT, respectively) are encoded by gene families SLC28 and SLC29

28. Adenosine is a naturally occurring nucleoside which is present in various forms in all cells of the body

29. A connection between visceral lipomatosis and protease inhibitors and lipoatrophy and nucleoside reverse transcriptase inhibitors has been hypothesised

30. Adenosine is a purine nucleoside that is derived from the breakdown of ATP, and Adenosine has many physiological functions

31. Concentrative nucleoside transporters (CNTs), members of the solute carrier (SLC) 28 transporter family, facilitate the salvage of nucleosides and …

32. Therefore, the key difference between adenosine and Adenine is that adenosine is a nucleoside, whereas Adenine is a nucleobase

33. Adenosine definition is - a nucleoside C10H13N5O4 that is a constituent of RNA and yields adenine and ribose on hydrolysis.

34. Virology adjective Referring to an agent or effect that counters a retrovirus noun A drug that counters or acts against a retrovirus, usually understood to be HIV; FDA-approved antiretrovirals include reverse transcriptase inhibitors, nucleoside analogues and protease inhibitors See Antiretroviral, Non-nucleoside reverse transcriptase inhibitor.

35. As part of the SAR series, we also prepared nucleoside analogs 7 (S-Constrained ethyl, S-cEt) and 8 (R-Constrained

36. Nucleoside Analogues (NA) constitute an important class of antimetabolites used in the treatment of hematological malignancies and, more recently, in solid tumors

37. Concentrative nucleoside transporters (CNTs) are responsible for cellular entry of nucleosides, which serve as precursors to nucleic acids and act as signaling molecules

38. What is Adenosine? Adenosine is a purine nucleoside that acts as a very useful ACLS Drug to often treat and diagnose stable narrow-complex SVT (Supraventricular Tachycardia)

39. Adenosine is a nucleoside that occurs naturally in all cells of the body. Chemically it is 6-amino-9-beta-D-ribofuranosyl-9-H-purine

40. Acyclovir definition is - a cyclic synthetic nucleoside C8H11N5O3 used especially to treat the symptoms of chicken pox, shingles, and the genital form of herpes simplex.

41. In the active site of these enzymes, the incoming nucleoside triphosphate base-pairs to the template: this allows polymerases to accurately synthesize the complementary strand of their template.

42. Concentrative nucleoside transporters play a vital role in the absorption and reabsorption of exogenous physiological nucleosides, and at the cellular level mediate transmembrane movement of nucleosides and analogues

43. Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases

44. Zidovudine (Azidothymidine, AZT) is a nucleoside analog reverse-transcriptase inhibitor (NRTI), a type of antiretroviral drug used for the treatment of HIV/AIDS infection.;IC50 value:;Target: NRTI; reverse-transcriptaseAZT is a thymidine analogue.

45. Concurrently, adrenergic stimulation of red blood cell Na+–H+ exchange, reduction of intracellular nucleoside triphosphates, swelling of red blood cells, and respiratory alkalosis all tend to increase oxygen affinity and capacity of hemoglobin.

46. Activation of nucleoside donors 5 by sulfuryl chloride followed by the addition of 5'-thionucleoside acceptors 3 yields 5'-thioformacetal dinucleotide analogs 6 with in situ trapping of liberated methanesulfenyl chloride with cyclohexene.

47. In another aspect of the invention, an abnormality reflected in increased response in one group of cytokines is treated by administering a nucleoside or other compound which increases response in another group of cytokines.

48. Acyclovir, an acrylic purine nucleoside analog, is a highly potent inhibitor of herpes simplex virus (HSV), types 1 and 2, and varicella zoster virus, and has extremely low toxicity for the normal host cells.

49. Backtracked and paused state is observed when all nucleoside triphosphates (NTPs) are present a t physiologically relevant con-centrations, but becomes more p revalent with unbalanced NTP levels, which may occur in vivo under conditions of metabolic stress

50. A new synthetic pathway to the carbocyclic nucleoside analogues (±)-aristeromycin (15) and its 5′-homo-derivative (17) has been developed starting form norborn-5-en-2-one using nucleophilic substitution of a sulfonate ester group by the aglycone.

51. Azt, in full azidothymidine, also called zidovudine, drug used to delay development of AIDS (acquired immunodeficiency syndrome) in patients infected with HIV (human immunodeficiency virus). Azt belongs to a group of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs).

52. The method for treating infection of cells by HIV comprises administering a composition comprising rHIV, which is produced $i(in vitro) from a recombinant mammalian cell-line, and treating with a nucleoside analog, such as Acyclovir or Gancyclovir.

53. The nucleoside Analogues are an important class of antiviral agents now commonly used in the therapy of human immunodeficiency virus (HIV) infection, hepatitis B virus (HBV), hepatitis C virus (HCV), cytomegalovirus (CMV), herpes simplex virus (HSV) and varicella-zoster (VZV) infection

54. Acyclovir is an antiviral drug, a synthetic nucleoside analogue, that has inhibitory activity (interferes with viral replication) against the herpes viruses, including herpes simplex 1 and 2 (cold sores and genital herpes), varicella -zoster (shingles and chickenpox), and Epstein-Barr virus (mononucleosis).

55. Adenosine is a natural chemical found inside all human cells and also a drug/supplement that is taken to manage many symptoms and improve energy levels. What is the difference between adenine and Adenosine? Adenosine is considered a purine nucleoside and a type of neurotransmitter

56. To this end we designed and prepared novel nucleoside analogs 4 (S-Constrained MOE, S-cMOE) and 5 (R-Constrained MOE, R-cMOE) where the ethyl chain of the 2'O-MOE moiety is Constrained back to the 4' position of the furanose ring

57. The difference between Adenine and adenosine is that Adenosine is a chemical compound that is a Nucleoside that occurs naturally in the cells of the human body, and on the other hand the Adenine is a chemical compound that occurs as a pure Nucleobase naturally in the cells of the human body

58. The molecule consists of an Adenine attached to a ribose via a β-N 9-glycosidic bond.Adenosine is one of four nucleoside building blocks to DNA and RNA, which are essential for all life.Its derivatives include the energy carriers adenosine mono-, di-, and triphosphate, also known as AMP/ADP/ATP.

59. Acyclic nucleoside analogs such as acyclovir, ganciclovir, penciclovir and the corresponding pro-drugs, i.e., valacyclovir, valganciclovir and famciclovir, respectively have been identified as inhibitors or antagonists of both telomerase (encoded by TERT) and reverse transcriptase encoded by L-1 (LINE-1) RT, and as useful for treating or preventing cancers induced or mediated by the two enzymes.

60. Pyrazomycin is a rare C‐nucleoside antibiotic containing a naturally occurring pyrazole ring, the Biosynthetic origin of which has remained obscure for decades.In this study we report the identification of the gene cluster responsible for pyrazomycin biosynthesis in Streptomyces candidus NRRL 3601, revealing that the StrR‐family regulator PyrR is the cluster‐situated transcriptional

61. Acyclovir is a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus family.After conversion in vivo to the active metabolite Acyclovir triphosphate by viral thymidine kinase, Acyclovir competitively inhibits viral DNA polymerase by incorporating into the

62. An antisense nucleic acid homolog having at least one nucleoside represented by general formula (1) in the same chain of a nucleic acid homolog having been modified or replaced at DNA, RNA or a phosphoric acid diester bond, wherein B represents adenin-9-yl, guanin-9-yl, hypoxanthin-9-yl, thymin-1-yl, uracil-1-yl or cytosin-1-yl; and X and Y are the same or different and each represents hydrogen, hydroxy, halogeno or lower alkoxy.

63. A process for producing a 2',3'-dideoxy-$g(b)-nucleoside in a simplified manner in a high yield, which comprises condensing 1-O-acetyl-5-O-(t-butyldiphenylsilyl)-2,3-dideoxy-2,2-di(phenylthio)-D-$i(glycero)-pentofuranose (IV), which is prepared from 5-(t-butyldiphenylsilyloxy)-2,2-di(phenylthio)-pentan-4-olide, with a pyrimidine derivative (V) in the presence of a Lewis acid catalyst, purifying the reaction product by chromatography into 1-[5-O-(t-butyldiphenylsilyl)-2,3-dideoxy-2,2-di(phenylthio)-$g(b)-D-$i(glycero)-pentofuranosyl] pyrimidine (III), hydrodesulfurizing the pyrimidine (III) into 1-[5-O-(t-butyldiphenylsilyl)-2,3-dideoxy-$g(b)-D-$i(glycero)-pentofuranosyl] pyrimidine (II), and deblocking the pyrimidine (II) into 2',3'-dideoxy-$g(b)-uridine (I) (wherein X represents oxygen and Y represents hydrogen).