Use "metastasized" in a sentence

1. Thyroid cancer metastasized to his brain.

2. That meant it was metastasized from somewhere.

3. It metastasized outward to the spine and muscles.

4. In view of the history, clinical and biochemical findings we diagnosed a recently metastasized functioning parathyroid carcinoma, which eight years previously has been labeled as a benign atypical thyroid adenoma. The patient underwent surgical resection of all detected metastases.