1. Most penile melanotic macules, angiokeratoma, fibroma and angioma have not to be treated.

2. The products include mandarin perch, California weever, melanotic shrimp, clean water crab, prawn and etc, . It gets great economic benefits.

3. Nomenclatures have historically been varied, including Apocrine cysts/tumors, 4 cystadenomatosis, ceruminous cystomatosis, 1,5 benign melanotic ceruminous gland adenomas 3 and ceruminous adenomas (multi-centric/focal), Apocrine hyperplasia

4. Most penile melanotic macules, angiokeratomas, fibromas and angiomas do not have to be treated; however, penile skin lesions may also be symptoms of other diseases, such as circinate balanitis in Reiter’s syndrome and multiple angiokeratomas in Fabry’s disease.