1. Representative examples include hydatidiform mole and Choriocarcinoma

2. A Choriocarcinoma is even rarer than a hydatidiform mole

3. Conclusion There is not much correlation between pathological classification and molecular genetics of hydatidiform mole.

4. Objective To study the relationship between the pathological classification and molecular genetics of hydatidiform mole.

5. AFP has an increasing importance in gynecology (gestational age, fetal distress syndrom, malformations, hydatidiform mole/chorion carcinoma).

6. Unlike the HYDATIDIFORM MOLE, Choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS)

7. Unlike a hydatidiform mole, a Choriocarcinoma is a malignant and more aggressive form of GTD that spreads into the muscle

8. About Choriocarcinoma Gestational trophoblastic disease is an aggressive, malignant, often metastatic (spreading to other organs) cancer in the womb which begins following a pregnancy (particularly one with hydatidiform mole), a miscarriage, or an abortion.