1. Penetrative puncture resulted in a faster decrease in disc height, lower glycosaminoglycan content, and higher grades of histologic degeneration.

2. A practical and effective method for extraction of glycosaminoglycan (GAG) from Bay scallop(Argopecten irradians Larmarck) was studied.

3. Significant induction of glycosaminoglycan, which is known to retain substantial water, and increased collagen production are most likely responsible for wrinkle effacement .

4. Integra® Bilayer Matrix Wound Dressing,Integra® Bilayer Wound Matrix is an advanced wound care device comprised of a porous matrix of cross-linked bovine tendon collagen and glycosaminoglycan and a semi-permeable polysiloxane (silicone layer)

5. INTEGRA™ Bilayer Wound Matrix Page 2 Product and Procedure Overview INTEGRA™ Bilayer Wound Matrix is an advanced wound care device comprised of a porous matrix of cross-linked bovine tendon collagen and glycosaminoglycan and a semi-permeable polysiloxane (silicone layer)