1. Erythema, scaling, and painful fissuring and cracking on palms and soles, especially involving the fingers and the toes.

2. Medically known as cheilitis, Chapped lips are characterized by peeling, fissuring and cracking of the lip skin, says Shari Marchbein, MD,

3. Angular cheilitis, also known as perlèche, is diagnosed clinically by the presence of inflammation, maceration and fissuring of the oral Commissures

4. Ainhum Fissuring in the fold between the toes or fingers followed by the development of a constricting band around the base of the digit, usually the little toe, which eventually leads to spontaneous amputation

5. Ainhum Fissuring in the fold between the toes or fingers followed by the development of a constricting band around the base of the digit, usually the little toe, which eventually leads to spontaneous amputation