1. Cementum Cementum is the first target for plaque bacteria attack in the process of root caries formation, and is still thought to be the most unpredictable area of an adhesive resin restoration

2. The Coleopterans are likely to be the first target to be controlled by the new generation of transgenics, the “RNAi-plants.” Diabrotica virgifera virgifera ( Western corn rootworm, WCR) is one of the most important agricultural pests, and this species, along with other Coleopterans, requires little effort to have genes silenced by RNAi