1. Fabry disease might be able to cause central and peripheral pain.

2. Symptoms including Adiaphoresis and angiokeratoma, corneal opacities (cornea verticillata), hearing loss, and abdominal pain are seen as clinical findings in the early stage of classic Fabry disease

3. Agas : Fabry disease is an X-linked lysosomal storage disorder resulting from deficient activity of the enzyme alpha-galactosidase A (alpha-Gal A) and the subsequent deposition of glycosylsphingolipids in tissues throughout the body; in particular, in the kidney, heart, and brain