1. Two common Alkaloids examined for in ergot are ergotamine and ergovaline.

2. In addition to the native alkaloids, a decomposition product of ergotamine was also detected.

3. Ergotamine is in a group of drugs called ergot Alkaloids (ER-got AL-ka-loids)

4. AIM: To compare the efficacies of sumatriptan injection (Sum) vs ergotamine and caffeine tablet (Erg) on migraine.

5. Acute treatment of migraine should include environmental isolation and analgesics such as acetylsalicylic acid or paracetamol; sometimes antiemetic drugs may be useful before. In refractory cases one should try ergotamine.

6. Chloroquine is known to induce neural damage. Moreover, some other compounds (ergotamine. ethaverine, analgetic preparations) may also be responsible for the drug-induced axonal dystrophy described in this study.