1. Bradykinin synonyms, Bradykinin pronunciation, Bradykinin translation, English dictionary definition of Bradykinin

2. Bradykinin, hypertension, and the cardiovascular system Bradykinin and hypertension

3. Bradykinin is metabolized by many different peptidases that play a major role in the control of Bradykinin levels.

4. These findings raise the question of whether Bradykinin mediates angioedema.We measured plasma Bradykinin in patients

5. Suggest that the Bradykinin Storm may be

6. Bradykinin also plays a crucial role in inflammation.

7. Bradykinin is a chemical that regulates blood pressure

8. Functional effects of endogenous Bradykinin in congestive heart failure

9. As Bradykinin accumulates, the effects start showing up

10. It has a role as a Bradykinin receptor B2 agonist

11. Because angiotensin converting enzyme (ACE) proteolytically inactivates Bradykinin, ACE

12. Bradykinin is a short-lived peptide, and degrades into inactive peptides

13. Bradykinin, an inflammatory mediator, sensitizes nociceptor peripheral terminals reducing pain threshold

14. In threshold doses kallidin proved to be more active than bradykinin.

15. It is a conjugate base of a [des-Arg(9)]-Bradykinin…

16. This is what researchers call a "Bradykinin storm." BI reported.

17. Bradykinin (9 aa, ~1 kDa) is encoded by the human KNG1 gene

18. However, Bradykinin also contributes to pathological states such as angioedema and inflammation

19. Adsorbent for bradykinin, method for eliminating the same by adsorption, and adsorber

20. Bradykinin is a protein that lowers blood pressure by widening blood vessels

21. Besides kallikrein, other proteases such as plasmin may also release Bradykinin.

22. Bradykinin promotes the synthesis and blocks the degradation of hyaluronic acid

23. Angiotensin-(1–7) induces Bradykinin-mediated hypotensive responses in anesthetized rats

24. Bradykinin is a bioactive hormone that’s involved in a variety of physiological processes

25. Bradykinin is a pro-inflammatory peptide that acts through G-protein-coupled receptors

26. Certain enzymes are capable of breaking down bradykinin (Angiotensin Converting Enzyme, Aminopeptidase P).

27. Bradykinin is also part of the DOMS reaction, delayed onset muscle soreness

28. Bradykinin A peptide that widens blood vessels (vasodilatation) and lowers blood pressure, increases capillary permeability and the secretion of saliva and mediates pain associated with inflammation. Bradykinin is inactivated by the angiotensin-converting enzyme

29. Bradykinin is a potent endothelium-dependent vasodilator, leading to the reduction in blood pressure

30. [des-Arg(9)]-Bradykinin is an eight-membered oligopeptide comprising Arg, Pro, Pro, Gly, Phe, Ser, Pro and Phe residues joined in sequence.It is an analogue of Bradykinin lacking the Arg residue at position 9

31. Bradykinin is involved in hereditary C1-inhibitor deficiency angioedema, in ACE inhibitor-related angioedema, and in idiopathic non-histaminergic angioedema, while Bradykinin is not related to allergen-dependent or idiopathic angioedema that are responsive to antihistamines.

32. Other articles where Bradykinin is discussed: hormone: Endocrine-like glands and secretions: …the blood and perhaps elsewhere; Bradykinin, for example, causes contraction of most smooth muscles and has a very potent action in dilating certain blood vessels

33. Bradykinin definition, a peptide hormone that dilates peripheral blood vessels and increases capillary permeability

34. Bradykinin, a biologically active peptide, is released by the breakdown of a high molecular weight kininogen by kallikreins Altamura et al (1999). Bradykinin is involved in plasma extravasation, bronchoconstriction, nociception, vasodilation, and inflammation Burch et al (1990).

35. In severe cases, the cycle seems to go into overdrive: The body can't stop producing Bradykinin

36. Bradykinin is a peptide found within the body that helps to enlarge or open blood vessels

37. Excessive Bradykinin leads to leaky blood vessels, allowing fluid to build up in the body’s soft tissues

38. Key words: bradykinin, B2 receptors, agonists, antagonists, smooth muscles, arachidonic acid cascade, indomethacin, BW 755C.

39. Bradykinin is an organic compound classified as a peptide that causes the dilation (enlargement) of blood cells

40. Jacobson’s team thinks a Bradykinin storm may instead be to blame for much of the viral pathogenesis.

41. Bradykinin (acetate) is a well-known 9-amino acid endogenous vasoactive peptide and a systemic vasodilator [1]

42. Zhang (2019) Direct Gαq Gating Is the Sole Mechanism for TRPM8 Inhibition Caused by Bradykinin Receptor Activation

43. In recent years, some new drugs have been introduced in the treatment of Bradykinin-mediated angioedema, such as

44. Bradykinin-mediated angioedema (eg, laryngeal angioedema) may be life-threatening because of resistance to corticosteroids and antihistamine drugs

45. ACE inhibitors block the enzymes needed to degrade Bradykinin in order to help control inflammation and blood pressure.

46. Other substances that act as bradykinin inhibitors include aloe and polyphenols, substances found in red wine and green tea.

47. Originally discovered by Rocha e Silva while investigating shock caused by snake venom, Bradykinin lowers blood pressure by vasodilation

48. In addition，PM2.5 could increase the viability of human airway smooth muscle cells (hASMCs), accompanied by increased expression of kallikrein 14 (Klk14), bradykinin 2 receptor (B2R), bradykinin secretion and cytosol calcium level, while kallikrein 14 gene knockdown could significantly Amelioratethe above response induced by PM2.5

49. Excess of the inflammatory molecule Bradykinin may explain the fluid build-up in the lungs of patients with coronavirus infections

50. Bradykinin StormMore lectures on drbeen.comLooking to support my educational work? Donate here:https://paypal.me/mobeensyed?locale.x=en_USExcerpt from Wikipe

51. Serum Bradykinin levels as a diagnostic marker in cervical cancer with a potential mechanism to promote VEGF expression via BDKRB2

52. Int J Oncol 2019;55:131 Direct Gαq Gating Is the Sole Mechanism for TRPM8 Inhibition Caused by Bradykinin Receptor Activation.

53. The peptide, Bradykinin, has cardiovascular effects similar to those of histamine and plays prominent roles in inflammation and nociception

54. Bradykinin is a physiologically and pharmacologically active nonapeptide produced in the body in response to many kinds of injuries

55. Definition of Bradykinin : a kinin that is formed locally in injured tissue, acts in vasodilation of small arterioles, is considered to play a part in inflammatory processes, and is composed of a chain of nine amino acid residues First Known Use of Bradykinin 1949, in the meaning defined above

56. The researchers believes the imbalance leads to the over-production of Bradykinin, which swoops in to keep blood pressure from getting too high

57. Bradykinin has important physiological actions related to the regulation of blood vessel tone and renal function, and protection from ischemia reperfusion injury

58. Fibroblasts treated with Bradykinin produce a rapid and important increase in ceramide which is followed by a transient rise in sphingosine content.

59. But Firazyr (icatibant), an inhibitor of Bradykinin signaling, is not effective in resolving these acute attacks, either because patients arrive at a hospital too

60. Bradykinin is a vasoactive peptide, nine amino acids in length, cleaved from high-molecular-weight or low-molecular-weight kininogen by tissue or plasma kallikrein

61. Many brands of blood pressure lowering medications help to enhance Bradykinin production or to keep it from lessening within the body due to certain conditions.

62. The discovery of bradykinin led to a new understanding of many physiological and pathological phenomena including circulatory shock induced by venoms and toxins.

63. The Bradykinin theory was outlined in a July research paper published in eLife, but it was recently featured in a widely read article published on Medium 's science website, Elemental.

64. Bradykinin is a nonapeptide messenger that is enzymatically produced from kallidin in the blood where it is a powerful but short-lived agent of arteriolar dilation (vasodilator) and increased capillary permeability

65. Bradykinin is a peptide (which is built from amino acids, similar to a protein, only smaller in size) that promotes inflammation, lowers blood pressure by dilating blood vessels, and plays a

66. Bradykinin is generated from the blood globulin kininogen HK, by the action of the kallikrein system in blood (related to the blood clotting cascade) but can also be generated in other tissues and organs

67. Bradykinin — the molecule involved in most angioedema attacks — also plays a part in a nonallergic type caused by angiotensin-converting enzyme (ACE) inhibitors, including migraine and blood pressure medications, a study found.

68. At the same time, it allows water to leak from the vessels into surrounding tissues, which increases inflammation in the area. Bradykinin helps your body to compensate for this movement of water by making you thirsty [ …

69. The bradykinin analogs described inhibit $g(a)-thrombin-induced and ADP-induced platelet activation and secretion, inhibit $g(a)-thrombin-induced calcium mobilization, and prevent $g(a)-thrombin from cleaving its platelet receptor.

70. The Bradykinin-Storm-induced leakage of fluid into the lungs combined with the excess hyaluronic acid would likely result in a Jello-like substance that is preventing oxygen uptake and carbon dioxide release in the lungs of severely affected COVID-19 patients

71. We now show that the B2 kinin receptor is expressed in rat dorsal horn neurons and that Bradykinin, a B2-specific agonist, augments AMPA- and NMDA-induced, and primary afferent-evoked EPSCs, and increases the frequency and amplitude of miniature EPSCs in superficial dorsal …

72. Bradykinin is a locally produced blood plasma protein which has a number of proinflammatory effects including stimulation of sensorimotor nerves, leading to pain and reflex responses (largely through B2 receptors), and CGRP and tachykinin release, leading to motor effects including plasma protein extravasation in skin and airways and to positive chrono- and inotropic effects in isolated atria.

73. Bradykinin là một trong các kinin huyết tương, có vai trò quan trọng trong phản ứng viêm (gây giãn mạch, tăng tính thấm mao mạch, và gây đau); cùng với histamine, leucotrien, prostaglandin, các kinin cũng là chất trung gian hóa học của quá trình viêm.

74. ブラジキニン（Bradykinin, BK）とは、ノナペプチド（9個のアミノ酸が連なった分子）であり、血圧降下作用を持つ生理活性物質の1種である。 キニノーゲンから血漿カリクレインやトリプシンによって作られる。 構造はArg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH。 肺に存在するキニナーゼ（アンジオテンシ …