1. Acetaminophen is a p-aminophenol derivative with analgesic and antipyretic activities

2. Acetaminophen is a p-aminophenol derivative with analgesic and Antipyretic activities

3. Patients with chronic hepatitis and with liver cirrhosis showed a decrease in the glucuronide and an increase in free N-acetyl-p-aminophenol after a dose of 1200 mg acetanilide.

4. It is believed that "fast acetylators" metabolize aniline predominantly by N-acetylation (to acetanilide), followed by aromatic hydroxylation (to N-acetyl-p-aminophenol), and subsequent conjugation to glucuronide or sulphate (DECOS, 1989).

5. An integrated nanocatalyst (INC), denoted [email protected](Fe), was synthesized by immobilizing a biocatalyst onto a metal–organic framework (MOF)-based catalyst, which can Cascadingly degrade organophosphate nerve agents to 4-aminophenol (4-AP) and result in a …

6. The N-acetylation of aniline (to acetanilide) is catalyzed by the hepatic N-acetyltransferase, while the aromatic hydroxylation of aniline (to o- or p-aminophenol) involves the cytochrome P-450 (mixed function oxidase) enzyme system (aniline hydroxylase).

7. Aminophenol derivatives represented by general formula (1), salts thereof or optical isomers thereof, and a gastrin receptor antagonist, a cholecystokinin receptor antagonist and a remedy for digestive tract diseases containing the same, wherein X represents O or S; A represents alkylene; R?

8. The reaction products:p-benzoquinone and ammonia, respectively, allow a quantitative determination ofp-aminophenol even in the presence of some inorganic reducing materials (sulfides, sulfites, etc.) provided the excess bromine is removed by means of phenol (iodometric method) or sodium sulfite (alkalimetric determination).

9. 12 patients with chronic hepatitis and 12 patients with liver cirrhosis as proved by laparascopy and histological examination received peroral doses of 800 or 1200 mg acetanilide. 12 healthy persons of the same age served as a controll. 2, 6 and 24 hrs after giving the dose free N-acetyl-p-aminophenol and its glucuronide were determined in the serum and in 24 hrs urine.