1. Rebound metabolic alkalosis is a transient alkalemia that is seen during recovery from NH4Cl-induced metabolic acidosis.

2. Decreases in H+-ions result in alkalemia and the corresponding disease conditions are either metabolic or respiratory alkalosis.

3. Alkalosis definition, a condition of the blood and other body fluids in which the bicarbonate concentration is above normal, tending toward alkalemia

4. If the pH of the blood is higher than 7.45, it is identified as alkalemia, the disease caused by Alkalosis.The major component in our blood is bicarbonate.

5. Our results show that the distal tubule microperfused in vivo during rebound metabolic alkalosis continues to reabsorb significant amounts of bicarbonate, despite the presence of systemic alkalemia that we have previously shown to be associated with distal tubule bicarbonate secretion.