transcriptase in English

noun

1

an enzyme that catalyzes the formation of RNA from a DNA template during transcription. Also called RNA polymer.

A chromosome-specific cosmid library was screened with the amplified 240-bp npkA fragment identified in the differential display-reverse transcriptase polymerase chain reaction procedure.

Use "transcriptase" in a sentence

1. Azt is a nucleoside reverse transcriptase inhibitor

2. Azt is a nucleoside analog reverse-transcriptase inhibitor

3. Azidothymidine (AZT, also called Zidovudine) is a nucleoside analog reverse-transcriptase inhibitor useful against the HIV virus

4. High-affinity ligands of insulin receptor antibodies, tachykinin substance p, hiv integrase and hiv-1 reverse transcriptase

5. Azt inhibits the enzyme (reverse transcriptase) that HIV uses to synthesize DNA, thus preventing viral DNA from forming.

6. A connection between visceral lipomatosis and protease inhibitors and lipoatrophy and nucleoside reverse transcriptase inhibitors has been hypothesised

7. Virology adjective Referring to an agent or effect that counters a retrovirus noun A drug that counters or acts against a retrovirus, usually understood to be HIV; FDA-approved antiretrovirals include reverse transcriptase inhibitors, nucleoside analogues and protease inhibitors See Antiretroviral, Non-nucleoside reverse transcriptase inhibitor.

8. Azidothymidine (AZT), a thymidine analogue, is a reverse transcriptase inhibitor against the HIV-1 virus. Azidothymidine has been shown to decrease CRISPR-mediated homology-directed repair (HDR) efficiency

9. The Antiretroviral agents most strongly associated with direct nephrotoxicity include the nucleotide reverse transcriptase inhibitor, tenofovir, and the protease inhibitor indinavir, although other agents have been implicated less frequently.

10. Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases

11. Zidovudine (Azidothymidine, AZT) is a nucleoside analog reverse-transcriptase inhibitor (NRTI), a type of antiretroviral drug used for the treatment of HIV/AIDS infection.;IC50 value:;Target: NRTI; reverse-transcriptaseAZT is a thymidine analogue.

12. Azt, in full azidothymidine, also called zidovudine, drug used to delay development of AIDS (acquired immunodeficiency syndrome) in patients infected with HIV (human immunodeficiency virus). Azt belongs to a group of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs).

13. Using semi-quantitative reverse transcriptase polymerase chain reaction we analyzed the ontogenic expression patterns of several nuclear receptors (estrogen receptors [ERα and β], androgen receptors [ARα and β], Ad4BP/SF-1 and Dax-1) and cytochrome P450 Aromatases (brain and ovarian types) in whole brain and gonads of the Nile tilapia

14. Acyclic nucleoside analogs such as acyclovir, ganciclovir, penciclovir and the corresponding pro-drugs, i.e., valacyclovir, valganciclovir and famciclovir, respectively have been identified as inhibitors or antagonists of both telomerase (encoded by TERT) and reverse transcriptase encoded by L-1 (LINE-1) RT, and as useful for treating or preventing cancers induced or mediated by the two enzymes.

15. HIV-1 protease cleaves Actin in vitro at amino acid residues 7-8, 66-67, 94-95, 105-106, 126-127, and 296-297: PubMed: gag-pol: Actin, one of the most abundant proteins of the cell, is hydrolyzed by the human immunodeficiency virus type 1 (HIV-1) protease during acute infection of cultured human T lymphocytes: PubMed: reverse transcriptase: gag-pol