thymidine in English
Both of these enzymes are involved in thymidine nucleotide biosynthesis.
Use "thymidine" in a sentence
1. Thymidine/Deoxyuridine Analytes (Plasma) TEST: 620173
2. Zidovudine (Azidothymidine, AZT) is a thymidine analogue
3. Thymidine-labeling indexing is determined by counting the number of tumor nuclei labeled on Autoradiographed sections after incubating the tumor cells with thymidine
4. These three hormones also robustly stimulated thymidine incorporation and inhibited drug - induced apoptosis.
5. The polymer is converted to the acid chloride form and condensed with thymidine derivatives.
6. Thymine combined with deoxyribose creates the nucleoside deoxythymidine, which is synonymous with the term thymidine.
7. Tritiated thymidine incorporation was measured using phenol–chloroform extractions; leucine incorporation was measured in trichloroacetic acid precipitates.
8. Kinetic data for blood basophils in rabbits were collected following pulse-labelling with intravenous injection of3H-thymidine.
9. The problem — mitosis or amitosis — is investigated with autoradiographic (3H-Thymidine) and electronicmicroscopic methods in new-born, juvenile and adult rabbits.
10. DNA synthesis as assessed by [(3)H]thymidine incorporation and cell counts were significantly reduced (by approximately 30%) in Adenos-transduced HUVECs
11. Specimens of placenta tissue from 39 normal and 31 pathological pregnancies (diabetes mellitus, toxemia, erythroblastosis and hydatiform mole) were incubated with tritiated thymidine.
12. By comparing the14C-thymidine incorporation with and without amethopterin in the incubation medium, the extent of participation of methylation for thymidylate formation is estimated.
13. The rate of dying off of the embryos was greatest when the3H-thymidine was injected into the amniotic cavity, and smaller when applied to the yolk.
14. The importance of a knowledge of the specific mode of action is discussed taking as example the increased incorporation of 3H-thymidine using Amethopterin and 5-Fluorouracil.
15. Azidothymidine (AZT), a thymidine analogue, is a reverse transcriptase inhibitor against the HIV-1 virus. Azidothymidine has been shown to decrease CRISPR-mediated homology-directed repair (HDR) efficiency
16. TAS-102, a novel Antimetabolite combination chemotherapy agent, consists of a rediscovered Antimetabolite agent, trifluorothymidine (trifluridine) combined with the metabolic inhibitor of thymidine phosphorylase, tipiracil, in a 1:0.5 molar ratio
17. A new in vitro method for estimating DNA synthesis times of human bone marrow cells is described.14C-thymidine incorporation rates under amethopterin are determined in individual cells by means of quantitative autoradiography.
18. Zidovudine (Azidothymidine, AZT) is a nucleoside analog reverse-transcriptase inhibitor (NRTI), a type of antiretroviral drug used for the treatment of HIV/AIDS infection.;IC50 value:;Target: NRTI; reverse-transcriptaseAZT is a thymidine analogue.
19. Except that the nucleotide thymidine (T) is found in place of uridine (U), they read the same as RNA Codons.However, mRNA is actually synthesized using the antisense strand of DNA (3' to 5') as the template
20. Direct measurements of the ribonucleoside and deoxyribonucleoside triphosphate pool sizes have been made, and the pathways and rates of metabolism of adenine, hypoxanthine, guanine, guanosirae, deoxyadenosine, and deoxyguanosine and of uridine, cytidine, deoxyeytidine, deoxyuridine, and thymidine have been determined.
21. The HSV-1-derived expression vectors are non-neurovirulent and do not spontaneously reactivate from latency, and they optionally contain a functional HSV thymidine kinase gene, which can enhance the effectiveness against cancer of drug treatment with gancyclovir or acyclovir.
22. The mutual interactions of Gd(III)tetraphenylporphyrin (GdTPP), Gd(III)tetramethylpyridylporphyrin (GdTMePyP), and the free base tetramethylpyridylporphyrin (H2TMePyP) with some nucleic bases (adenine, thymine, uracil, and cytosine) and their N-glycoside derivatives (adenosine, thymidine, uridine, and cytidine) have been studied by spectrophotometric titration in mixed methanol-ammonia-water solutions.
23. In 5 cases of polycythaemia vera and 2 cases with other myeloproliferative disorders accompanied by thrombocythaemia (megakaryocytic myelosis), the megakaryocytes were differentiated and studied by use of the combined application of cytophoto-metric determination of the DNA content and autoradiography with tritiated thymidine (3H-TdR) in vitro.
24. Provided are ribosome binding sites having an increased number of adenine (A) and thymidine (T) residues as compared to the naturally occurring ribosome binding sites from which they are derived or to which they are related, which allow high level expression of genes encoding heterologous polypeptides, particularly somatotropins, operatively linked thereto.
25. Acyclovir is a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus family.After conversion in vivo to the active metabolite Acyclovir triphosphate by viral thymidine kinase, Acyclovir competitively inhibits viral DNA polymerase by incorporating into the
26. The rate of the de-novosynthesis of DNA provides an estimate of the growth of those malignant tumors. Comparing the rate of DNA synthesis and the sensitivity of more than 200 different malignant tumors to alkylating agents in vivo and in vitro, only such neoplasms with significantly high [14C] thymidine and [14C] deoxyuridine incorporation into DNA seem to respond to therapy with alkylating agents, e. g. Cyclophosphamide (Endoxan).