thrombin in English

noun
1
an enzyme in blood plasma that causes the clotting of blood by converting fibrinogen to fibrin.
In addition to its role in activation of fibrin clot formation, thrombin plays an important regulatory role in coagulation.

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Below are sample sentences containing the word "thrombin" from the English Dictionary. We can refer to these sentence patterns for sentences in case of finding sample sentences with the word "thrombin", or refer to the context using the word "thrombin" in the English Dictionary.

1. Thrombin activity Assayan assay for thrombin activity was designed according to a previously described procedure (35)

2. The bradykinin analogs described inhibit $g(a)-thrombin-induced and ADP-induced platelet activation and secretion, inhibit $g(a)-thrombin-induced calcium mobilization, and prevent $g(a)-thrombin from cleaving its platelet receptor.

3. 4 words related to Coagulase: enzyme, thrombin, chymosin, rennin

4. An electrochemical and Colorimetric dual-readout method is described for the determination of thrombin

5. This invention relates to novel biologically active molecules which bind to and inhibit thrombin.

6. The use of heparin could be avoided altogether by Anticoagulating with a direct thrombin inhibitor

7. Anticoagulant drugs fall into three groups: inhibitors of clotting factor synthesis, inhibitors of thrombin and antiplatelet drugs.

8. Dilute thrombin in Barbitone buffer to a concentration of about 20 National Institutes of Health (NIH) u/ml

9. Thrombin aggregation proved to be normal with the higher concentrations, whereas it was defective with the lower ones.

10. Adrenoceptor α 2A signalling Countervails the taming effects of synchronous cyclic nucleotide-elevation on thrombin-induced human platelet activation and aggregation Adrenoceptor α 2A signalling Countervails the taming effects of synchronous cyclic nucleotide-elevation on thrombin-induced human platelet activation and aggregation

11. Methods include viscoelastic Assays, thrombin generation Assays and transmittance waveform analysis, a variation on one-stage clot Assays.

12. The resulting active thrombin may be captured on an ion exchange chromatography medium or an affinity chromatography medium.

13. Adrenoceptor α 2A signalling Countervails the taming effects of synchronous cyclic nucleotide-elevation on thrombin-induced human platelet activation and aggregation

14. Chemistry, Biological Chemistry, Biological Sciences, Thrombin Characterization of type IV collagen NC1 monomers and Goodpasture antigen in human renal basement membranes

15. Coagulase An enzyme secreted by the micro-organism Staphylococcus aureus that causes clotting in blood plasma by converting prothrombin to thrombin

16. For this reason, heparin's activity against thrombin is size-dependent, with the ternary complex requiring at least 18 saccharide units for efficient formation.

17. Adipose tissue biocomposites in certain embodiments include two layers, a first layer having an adipose tissue component and a second layer having fibrin and thrombin.

18. Ex vivo platelet aggregation was induced using arachidonic acid (ASPI test), as well as thrombin receptor activating peptide (TRAP test) and adenosine diphosphate (ADP test).

19. (ii) to 1 ml add a suitable amount of thrombin or calcium chloride ; coagulation occurs, which can be accelerated by incubation at 37 C.

20. Disseminated Intravascular Coagulation: APTT PT Thrombin Time (TT) Antithrombin activity Fibrinogen clottable D-dimer Peripheral blood smear morphology Thrombotic hypercoagulable: PT APTT Mixing studies

21. Method. The aneurysm was punctured under continuous color duplex ultrasound control and human thrombin was injected into the aneurysm sac until it was completely thrombosed.

22. This protective reaction, maintaining the blood in a fluid state in the vascular bed when thrombin arises in it, is brought about by the physiological Anticoagulating system.

23. To recover biologically active DS4, the purified fusion protein was cleaved using thrombin protease; the liberated DS4 was shown to be Bactericidally active against an indicator strain.

24. In 20 patients with acute leukemia the thrombin-mediated fibrin monomer complexes (SFMC) were determined before and after remission induction chemotherapy for several weeks to assess the extent of hypercoagulability.

25. It was found to affect trypsin, chymotrypsin, plasmin, thrombin and some human skin proteases, especially those which hydrolyze casein, N-acetyl-l-tyrosine ethyl ester·HCl (ATEE) andl-tyrosine ethyl ester·HCl (TEE) at around pH 8.0.

26. Coagulase An enzyme secreted by the micro-organism Staphylococcus aureus that causes clotting in blood plasma by converting prothrombin to thrombin. This ability probably contributes to the tendency of the organism to form abscesses

27. Tests made before and after operation included Quick’s test, partial thromboplastin time (PTT), Thrombin time, fibrinogen (factor I), prothrombin (factor 11), and pro-accelerin (factor V), as well as WBC and RBC counts to exclude any disturbances due to intraoperative hemorrhage.

28. The invention relates to prodrugs of pharmacologically active, five-membered heterocyclic amidines from which in vivo compounds are obtained, these compounds being competitive inhibitors of trypsin-type serin proteases, especially thrombin and kininogenases such as kallikrein.

29. In the present work we investigated the effect of serine esterase inhibitors such as 2-nitro-4-carboxyphenyl N,N-diphenylcarbamate (NCDC) and phenylmethylsulfonyl fluoride (PMSF), as well as the effect of mepacrine on thrombin-induced mobilization of arachidonic acid (AA) in human platelets.

30. To assess blood coagulation and fibrinolytic activity in congenital heart disease, the platelet count, plasma clotting times (thromboplastin time, partial thromboplastin time, thrombin time) as well as the coagulation (thrombelastography) and activity of the proactivator-plasminogen-complex of whole blood were determined prospectively in 500 patients; 55% of whom had acyanotic and 45% cyanotic lesions.