pyrimidine in English
Second, there is no branch in the pyrimidine synthesis pathway.
Use "pyrimidine" in a sentence
1. Anthelmintic; pyrimidine-derivative
2. Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine.
3. Summary: Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family
4. Alloxan is an oxygenated pyrimidine and toxic analog of glucose
5. Pyrimidine derivatives for the treatment of abnormal cell growth
6. Anabolism of fluorouracil to pyrimidine nucleotide analogues is required for its cytotoxic effects and pyrimidine catabolism is important in the regulation of fluorouracil availability and its subsequent Anabolism
7. Neutral or acid cadmium solutions react with a mixture of pure pyrimidine with sodium chloride or with acid pyrimidine solutions to yield colorless quadratic or rectangular crystals or laminated crystal aggregates or rosettes.
8. Triazolo [4,5-d] pyrimidine compounds for treatment of abdominal aortic aneurysms
9. Three subgroups of Antimetabolites are used: folic acid, pyrimidine, and purine analogues.
10. Azines with two nitrogen atoms in the ring are called diAzines—for example, pyrimidine (I
11. 22 Study on the synthesis of 2 - diethylamino - 6 - methyl - 4 - hydroxy pyrimidine.
12. 1,2,4-TRIAZOLO[1,5-c]PYRIMIDINE HETEROCYCLIC ANALOGUES HAVING ANTAGONISTIC ACTIVITY ON ADENOSINE A¿2?
13. Alloxan is an oxygenated pyrimidine derivative. It is present as Alloxan hydrate in aqueous solution
14. Several 7-methyl-5-alkyl-2-vinylpyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-diones were prepared.
15. Antimetabolite Pyrimidine Analog: Intravenous: July 25, 2011 In Use: 68001-0282-22: 68001-0282: Gemcitabine Hydrochloride: Gemcitabine Hydrochloride: 38.0 mg/mL: Chemotherapy Antimetabolite Pyrimidine Analog: Intravenous: July 25, 2011 In Use: 68001-0282-25: 68001-0282: Gemcitabine Hydrochloride: Gemcitabine Hydrochloride: 38.0 mg/mL
16. A process for producing a 2',3'-dideoxy-$g(b)-nucleoside in a simplified manner in a high yield, which comprises condensing 1-O-acetyl-5-O-(t-butyldiphenylsilyl)-2,3-dideoxy-2,2-di(phenylthio)-D-$i(glycero)-pentofuranose (IV), which is prepared from 5-(t-butyldiphenylsilyloxy)-2,2-di(phenylthio)-pentan-4-olide, with a pyrimidine derivative (V) in the presence of a Lewis acid catalyst, purifying the reaction product by chromatography into 1-[5-O-(t-butyldiphenylsilyl)-2,3-dideoxy-2,2-di(phenylthio)-$g(b)-D-$i(glycero)-pentofuranosyl] pyrimidine (III), hydrodesulfurizing the pyrimidine (III) into 1-[5-O-(t-butyldiphenylsilyl)-2,3-dideoxy-$g(b)-D-$i(glycero)-pentofuranosyl] pyrimidine (II), and deblocking the pyrimidine (II) into 2',3'-dideoxy-$g(b)-uridine (I) (wherein X represents oxygen and Y represents hydrogen).
17. Alloxan [2,4,5,6-tetraoxypyrimidine; 5,6-dioxyuracil] is a pyrimidine derivative of uric acid, first discovered in 1818 by Brugnaletti and then again in 1838 by Wohler
18. But the most noticeable feature is a unique modified base, queuine or Q, as the first letter of Anticodons, corresponding to the wobble site pyrimidine
19. Alloxan [2,4,5,6-tetraoxypyrimidine; 5,6-dioxyuracil] is a pyrimidine derivative of uric acid, first discovered in 1818 by Brugnaletti and then again in 1838 by Wohler
20. 25 Thymine: Organic compound of the pyrimidine family, often called a Base, consisting of a ring containing Both nitrogen and carbon atoms, and a methyl group.
21. Alloxan An oxygenated pyrimidine derivative, which is a toxic glucose analogue that induces experimental diabetes by selectively destroying pancreatic beta cells by superoxide production. Segen's Medical Dictionary
22. An AP site (apurinic/apyrimidinic site), also known as an Abasic site, is a location in DNA that has neither a purine nor a pyrimidine base
23. S phase-specific Antimetabolite (of pyrimidine) that is converted to a 5'-mononucleotide (AraCMP), and then to AraCTP, which competitively inhibits DNA polymerase and results in blockade of DNA synthesis
24. Acriflavine showed better binding affinity toward alternating polymer (RYR, R=purine, Y=pyrimidine) as compared to nonalternating ones (RR, YY) showing the heterogeneity in binding based on the DNA base composition
25. Alloxan is a thermally stable white solid with an unusual structure. Its formal name is 2,4,5,6 (1 H,3 H)-pyrimidinetetrone, indicating that it has a pyrimidine ring structure with four carbonyl groups
26. The next step leading to the eventual formation of nucleic acids and proteins , namely the formation of nudeotides ( purine or pyrimidine - f sugar + phosphate ) and peptides ( amino acids linked to one another ) has also been demonstrated in the laboratory .
27. A heterocyclic substituted Acardite derivate and use thereof namely compounds in the general formula (1) or the general formula (2) or pharmaceutically acceptable salts thereof, wherein A is monosubstituted or polysubstituted quinoline, isoquinoline, quinazoline, pyrrole, pyrimidine.
28. Antisenses against WT1 which comprise oligonucleotide derivatives containing 1 or more sugar-modified nucleotide analog units represented by the following general formula (2) wherein B represents a pyrimidine nucleic acid base, a purine nucleic acid base or an analog thereof.
29. Since the novel 2,7-substituted thieno[3,2-d]pyrimidine compound exhibits superior inhibition activity against various protein kinases involved in growth factor signal transduction, it is useful as an agent for preventing or treating diseases caused by abnormal cell growth.
30. a nitrogenous base and a phosphate group b a nitrogenous base and a pentose sugar Anitrogenous bag, a phosphate group, and a pentose sugar a phosphate group and an adenine or uracil a pentose sugar and a purine or pyrimidine d
31. Azine [ ăz ′ēn′, ā ′zēn′ ] Any of various organic compounds, such as pyridine or pyrimidine, that have a ring structure like that of benzene but with one or more carbon atoms replaced by a nitrogen atom. Azines are heterocyclic compounds.
32. Disclosed are a 2,4,7-substituted thieno[3,2-d]pyrimidine compound having a protein kinase inhibition activity, a pharmaceutically acceptable salt, and a pharmaceutical composition for prevention and treatment of diseases caused by abnormal cell growth comprising the compound as an effective ingredient.
33. Auxotrophy for pyrimidines, resulting from blockage of the de novo pyrimidine biosynthetic pathway at the orotidine 5′-phosphate decarboxylase level (encoded by URA3 or corresponding ortholog in non-yeast species) or at the orotate phosphoribosyltransferase level (encoded by URA5 or homologs), is one of the most used among microbes [,, ].
34. The present invention discloses a heterocyclic substituted Acardite derivate and application thereof, namely compounds of the general formula (1) or the general formula (2) or pharmaceutically acceptable salts thereof, wherein A is monosubstituted or polysubstituted quinoline, isoquinoline, quinazoline, pyrrole or pyrimidine, and the substituent is halogen, C 1-5 alkyl, C 1-5 …
35. The present invention discloses a heterocyclic substituted Acardite derivate and application thereof, namely compounds of the general formula (1) or the general formula (2) or pharmaceutically acceptable salts thereof, wherein A is monosubstituted or polysubstituted quinoline, isoquinoline, quinazoline, pyrrole or pyrimidine, and the substituent is halogen, C 1-5 alkyl, C 1-5 haloalkyl, C 1-5
36. The present invention relates to an N-Phenyl-2-pyrimidine-aminine derivative showing a superior effect on lung cancer, gastric cancer, colon cancer, pancreatic cancer, hepatoma, prostatic cancer, breast cancer, chronic or accute leukemia, hematologic malignancy, encephalophyma, bladder cancer, rectal cancer or cervical cancer, etc. of warm blooded animals and its salt.
37. The present invention relates to certain 2-(2,4,5-substituted-Anilino)pyrimidine compounds and pharmaceutically acceptable salts thereof which may be useful in the treatment or prevention of a disease or medical condition mediated through certain mutated forms of epidermal growth factor receptor (for example the L858R activating mutant, the Exon19 deletion activating mutant and the T790M
38. On the basis of current evidence, the following important IEM leading to nonspecific MR or to conditions with MR as the predominant clinical presentation are highlighted: creatine deficiency syndromes (in particular creatine transporter deficiency), mucopolysaccharidoses III (in particular IIIB), β-mannosidosis, specific organic acidurias, homocystinuria, CDG (congenital disorder of glycosylation), and specific disorders of purine and pyrimidine metabolism.
39. : a substance that is structurally similar to a metabolite (such as a coenzyme) and that serves to inhibit a particular cellular function (such as DNA synthesis) by interfering with or blocking the metaboliteʼs action From the start [Gertrude] Elion concentrated her research on using purine and pyrimidine Antimetabolites to interfere with the synthesis of nucleic acids …
40. The invention relates to the use in non-linear optics of azo dyes of formula I and the use of polymers containing azo dyes which include as characteristic monomer units bivalent groups derived from an azo dye of formula (I) wherein: D represents the residue of a diazo component derived from an aniline or from a five-membered aromatic heterocyclic amine whose heterocyclic ring includes one to three heteroatoms chosen from the group nitrogen, oxygen and sulphur and which can be anellated by a benzene, thiophene, pyridine or pyrimidine ring; R?