phentolamine in English

noun
1
a synthetic compound used as a vasodilator, especially in certain cases of hypertension.
Agitation and anxiety can be controlled with benzodiazepines, and hypertension with labetalol, phentolamine , or nitroprusside.

Use "phentolamine" in a sentence

Below are sample sentences containing the word "phentolamine" from the English Dictionary. We can refer to these sentence patterns for sentences in case of finding sample sentences with the word "phentolamine", or refer to the context using the word "phentolamine" in the English Dictionary.

1. Contractions were blocked by phentolamine and were abolished following pretreatment with reserpine.

2. This cardiostimulating effect was inhibited by the α-adrenolytic drug phentolamine (10−6 moles/kg).

3. Alpha Blockers that may have these side effects include yohimbine, phenoxybenzamine, and phentolamine

4. Following denervation of the liver and α adrenoreceptor blockade (3 mg phentolamine, intraportal) the liver compensation was unaltered.

5. Yohimbine and Phentolamine were investigated as adrenolytic drugs. Yohimbine depressed the cocaine hyperthermia in doses which had no hypothermic effect if given alone.

6. It has been observed in rabbits that hypotension caused by haemorrhagic orendotoxic shock could be reversed by injecting naloxone,(sentencedict .com) phentolamine or cinanserineinto the lateral cerebroventricle.

7. They appeared to involve alpha-adrenoreceptors, since responses to 10-7 M norepinephrine were unaffected by 10-6 M propranolol, but those to 10-7 and 1.24 × 10-6 M norepinephrine were abolished by 10-6 and 1.78 × 10-5 M phentolamine, respectively (based on 48 fetuses).

8. In vitro, i. e. upon incubation with epididymal adipose tissue of rats, the lipolytic effect of norepinephrine was inhibited by both α- and β-adrenolytics. To obtain 50% inhibition of a standard dose of norepinephrine (6×10−7 M), however, more than 100 times higher concentrations of the α-adrenolytics phentolamine or phenoxybenzamine were required as compared to the β-adrenolytics Kö 592 or propranolol.