oncogene in English

noun
1
a gene that in certain circumstances can transform a cell into a tumor cell.
Thus the presence of p53 mutation may trigger precipitate the derailment of the cell cycle machinery, rendering cells susceptible to additional aberrations in other important oncogenes and tumour suppressor genes.

Use "oncogene" in a sentence

Below are sample sentences containing the word "oncogene" from the English Dictionary. We can refer to these sentence patterns for sentences in case of finding sample sentences with the word "oncogene", or refer to the context using the word "oncogene" in the English Dictionary.

1. The EGF receptor is a product of the erb-B oncogene.

2. The GRO1 oncogene (melanoma growth-stimulating activity alpha)_has been localized in region 4q21.

3. Exons 10, 11, 13, 14, 15 and 16 of the RET proto-oncogene were amplified in polymerase chain reactions.

4. Conclusion:The effect of Weiyankang plus gastrone on precancerosis of gastric cancer may due to repress the abnormal expression of oncogene proteins in gastric mucosa.

5. Bitt has developed a platform for targeting the tumor necrosis factor receptor 2 (TNFR2) oncogene and the potent population of TNFR2 Tregs in the tumor microenvironment.

6. On the basis of the Bicyclic pyridopyrimidinone framework of the first-in-class clinical KRAS G12C inhibitor AMG510, a sc … KRAS is the most commonly altered oncogene of the RAS family, especially the G12C mutant (KRAS<sup>G12C</sup>), which has been a promising drug target for many cancers.