nicotinic in English
adjective
['nɪkə'tɪnck ,-tɪːnɪk]
containing nicotine; pertaining to nicotine
Use "nicotinic" in a sentence
1. - Nicotinic Acetylcholinic receptors
2. The imidazothiazoles are nicotinic Anthelmintics that act as agonists at nicotinic acetylcholine receptors of nematodes
3. Nicotinic acetylcholine receptor sub-type selective amides of diazabicycloal kanes
4. Acetylcholine is the endogenous agonist at muscarinic and nicotinic cholinergic receptors
5. Biomarkers predictive of responsiveness to alpha 7 nicotinic acetylcholine receptor activator treatment
6. Pharmaceutical or cosmetic composition containing nicotinic acid adenine dinucleotide phosphate or derivative thereof
7. Neuronal nicotinic Acetylcholinic receptors (nAChR) are promising targets for the development of novel analgesics
8. 2-phenyl-5-amino-1,3,4-oxadiazoles and their use as nicotinic acetylcholine receptor ligands
9. (-)-Bebeerine is described to noncompetitively block neuromuscular transmission through interaction with the nicotinic acetylcholine receptor
10. The Analgesic properties of nicotine have generated attempts to develop compounds targeting nicotinic acetylcholine receptors (nAChRs)
11. Neuronal nicotinic Acetylcholinic receptors (nAChR) are promising targets for the development of novel analgesics
12. Neuronal nicotinic Acetylcholinic receptors (nAChR) are promising targets for the development of novel analgesics
13. It also inhibits the AMPA receptor and nicotinic acetylcholine receptors, and activates certain K2P channels.
14. 7 Vitamin B3 comes in two basic forms - niacin (also called nicotinic acid) and niacinamide (also called nicotinamide).
15. The compounds are useful in the positive modulation of the alpha 7 nicotinic acetylcholine receptor (α7nAChR).
16. Bebeerine: A cyclic natural alkaloid which noncompetitively blocks neuromuscular transmission by interacting with the nicotinic acetylcholine receptor
17. Growth and sporulation of all the strains appeared to be independent of aneurine, nicotinic acid, pantothenic acid, pyridoxin and riboflavin.
18. Summary: The protein encoded by this gene promotes functional expression of homomeric nicotinic Acetylcholine receptors at the cell surface
19. Protein Subunit Gene Gene locus Phenotype; Neuronal nicotinic Acetylcholinic receptor: α2-subunit: CHRNA2: 8p21: ADNFLE: α4-subunit: CHRNA4: 20q13: ADNFLE: β2-subunit
20. The Curare-induced subconductance state of the nicotinic acetylcholine receptor (AChR) of mouse skeletal muscle was examined using the patch-clamp technique
21. The three vitamin precursors used in these salvage metabolic pathways are nicotinic acid (NA), nicotinamide (Nam) and nicotinamide riboside (NR).
22. Bupropion is a weak blocker of the neuronal uptake of serotonin, dopamine and norepinephrine and is a central nicotinic acetylcholine receptor antagonist.
23. The compounds of the invention are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters.
24. After discontinuation of azathioprine therapy and despite continuing therapy with cortisone, the KS progressed and autoantibody levels against the nicotinic acetylcholine receptor increased.
25. Using Kö 592 — or any potent β-adrenolytic — and nicotinic acid resp. it is thus possible to differentiate between adrenergic and nonadrenergics mechanisms leading to lipolysis.
26. The present invention relates to a use of nicotinic acid adenine dinucleotide phosphate or a derivative thereof for promoting the differentiation of keratinocytes into fibroblasts.
27. The present invention relates to novel diazabicycloalkane derivatives, which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters.
28. 7¿ are various substituents as selective modulators of the nicotinic acetylcholine receptor useful in the treatment of pain, Alzheimer's disease, memory loss or dementia or loss of motor function.
29. In contrast, both the effects of norepinephrine and ACTH were inhibited to about the same degree by the α-adrenolytic phenoxybenzamine and completely blocked by pretreatment with nicotinic acid.
30. New mutations in the genes encoding for the neuronal nicotinic acetylcholine receptors helped link these genes to a form of epilepsy, thus opening up new avenues for drug design.
31. These compounds have good affinity for ($g(a)4$g(b)2 nicotinic acetylcholine receptors and activate the same to thereby exert a preventive or therapeutic effect on cerebral dysfunction.
32. Pigs, honey badgers, mongooses, and hedgehogs all have mutations in the nicotinic acetylcholine receptor that prevent the snake venom α-neurotoxin from binding, though those mutations developed separately and independently.
33. For example, the enzyme nicotinamidase, which converts nicotinamide to nicotinic acid, is a target for drug design, as this enzyme is absent in humans but present in yeast and bacteria.
34. Should we be concerned? Drugs with anticholinergic activity (also known as Anticholinergics) prevent acetylcholine from binding to muscarinic and nicotinic receptors, which might result in numerous adverse drug events, especially in older adults
35. The behaviour of blood glucose during infusion of nicotinic acid together with the daily insulin dosage permitted a metabolic distinction to be made between diabetics of the stable and unstable (‘brittle’) type.
36. The nicotinic Anticholinergic mecamylamine, along with other antidepressants (selective serotonin reuptake inhibitors, commonly known as “SSRIs”), has been reported to improve treatment-resistant depression (TRD) according to two Phase-II clinical trials
37. A novel product obtained by reacting an alkalimetal salt of nicotinic acid with a trivalent chromium salt and having glucose tolerance factor activity, a process for its production and a method for its use, are disclosed.
38. Beside the well known diminution of portal flow by vasopressin, which is extreme in anaesthetised minipig, there could be shown a remarkable diminution by high intravenous doses of nicotinic acid too without significant changes of systemic blood pressure and heart rat.
39. When lipolysis in adipose tissue was blocked by 0.5 g of nicotinic adic/hour the triglyceridefatty acids reached only 116.2 % after 12 hours, with a decrease in oleic acid, which is present in adipose tissue to a higher degree than in plasma triglycerides.
40. Based on evidence from Autosomal Dominant NFLE, a genetic disorder with mutations in nicotinic acetylcholine receptors(nAchR), we hypothesise that arousal parasomnias and NFLE both, have abnormal arousal mechanisms in the dorsal cholinergic arousal branch triggering peculiar motor patterns in the medial frontal lobe regions.
41. Acute coronary syndrome As with other nicotinic acid medicinal products, caution should be used when Trevaclyn is used in patients with unstable angina or in the acute phase of an MI, particularly when such patients are also receiving vasoactive medicinal products such as nitrates, calcium channel blockers, or adrenergic blocking agents
42. METHODS: In a prospective study on 12 nerves at risk, the electromyogram was recorded with the computerized Neurosign100® system to (i) estimate the nerve conduction velocity, (ii) to compare the magnitude of the response after vagal and recurrent nerve stimulation and (iii) to document the effects of a nicotinic acetylcholine receptor antagonist.
43. Regarding its ecological importance, alkaloid Biosynthesis is a complex process that involves several enzymatic steps ().Nicotine has two ring moieties, a pyrrolidine ring and a pyridine ring, derived from two branch pathways (18, 27).The pyridine ring of nicotine is derived from nicotinic acid, whereas the pyrrolidine ring originates from polyamine putrescine metabolism, which is gradually
44. Under hydrothermal conditions, three copper coordination polymers, [Cu 1.5 (ina)(Btch)]·H 2 O (1), [Cu 2 (ina) 2 (bdc) 0.5 (μ 3-OH)] (2), and [Cu(ina)(na)] (3), were prepared from Cu(NO 3) 2 ·2.5H 2 O and a combination of pyridinecarboxylic acid {4-pyridinecarboxylic (isonicotinic acid, inaH) or 3-pyridinecarboxylic (nicotinic acid, naH)} and multicarboxylic acid {1,3-benzenedicarboxylic
45. The present invention provides an eperisone pharmaceutical composition having improved preservability and pH stability, the composition containing 20-60 wt% of eperisone or a pharmaceutically acceptable salt thereof; 1-30 wt% of at least one acidifier selected from D-glucaric acid, D-glucoascorbic acid, gluconic acid, D-glucuronic acid, gluconolactone, glucuronolactone, glutamic acid, itaconic acid, caffeic acid, glycyrrhizic acid, ethane sulfonic acid, benzene sulfonic acid, dehydroascoribic acid, salicylic acid, salicyl sulfonic acid, gallic acid, nicotinic acid, and chlorogenic acid; 0.3-8 wt% of a binder; and 10-80 wt% of a diluent.