macrocyclic in English

adjective
1
of, relating to, or denoting a ring composed of a relatively large number of atoms, such as occurs in heme, chlorophyll, and several natural antibiotics.
The polar head is a macrocyclic lactone ring containing nine amino acid residues, three of which have positive charges, whereas one has negative charge.

Use "macrocyclic" in a sentence

Below are sample sentences containing the word "macrocyclic" from the English Dictionary. We can refer to these sentence patterns for sentences in case of finding sample sentences with the word "macrocyclic", or refer to the context using the word "macrocyclic" in the English Dictionary.

1. Substituted alicyclic-aliphatic amine-containing macrocyclic immunomodulators

2. [Epub ahead of print] Solution conformations explain the Chameleonic behaviour of macrocyclic drugs.

3. ‘Chameleonic’ behavior is known to be important for the bioavailability of certain macrocyclic drugs

4. Novel aldehyde acetal based processes for the manufacture of macrocyclic depsipeptides and new intermediates

5. In the non-Arsenical treatment protocol, doxycycline and macrocyclic lactones act synergistically against microfilariae and immature worms 6,12

6. The grapheme modified by a macrocyclic compound is used as the catalyst and is used for catalyzing the oxygen reduction of batteries under acidic, neutral and alkaline conditions.

7. Key to the pharmaceutical utility of certain macrocyclic drugs is a 'Chameleonic' ability to change their conformation to expose polar groups in aqueous solution, but bury them when traversing lipid membranes

8. We found that the PA3944 enzyme Acetylates both polymyxin B and colistin on a single diaminobutyric acid residue closest to the macrocyclic ring of the antimicrobial peptide and determined the PA3944 crystal structure

9. The methanogen Methanosalsum natronophilum AME2 T had the most complex diether lipid composition of any of the 13 strains, including hydroxy Archaeol and macrocyclic Archaeol which we surmise is an order-specific membrane adaption.

10. Abstract Several Combinatorial methods have been developed to create focused or diverse chemical libraries with a wide range of linear or macrocyclic chemical molecules: peptides, non-peptide oligomers, peptidomimetics, small-molecules, and natural product-like organic molecules.