genotoxic in English

adjective

pertaining to a substance that by poisoning DNA may cause mutation or cance

Use "genotoxic" in a sentence

1. Aldicarb is neither genotoxic nor carcinogenic.

2. As Aflatoxins are known to be genotoxic and carcinogenic,

3. In addition, different sources of genotoxic stress induced differential modulations of p53 affinity.

4. Adenosine was negative for genotoxic potential in the Salmonella (Ames Test) and mammalian Microsome Assay

5. A) Aldrin has been genotoxic at the level of primary DNA damage, mutagenicity, and chromosome aberrations

6. The majority of genotoxicity studies performed in the dark do not reveal a genotoxic potential of #-ALA

7. Genotoxicity Toxicity Sorafenib demonstrated positive genotoxic effects with the in vitro chromosome aberration test with Chinese hamster cells.

8. Aflatoxins are considered to be genotoxic carcinogens that induce tumors in the liver of animals and humans

9. Genotoxicity Sorafenib demonstrated positive genotoxic effects with the in vitro chromosome aberration test with Chinese hamster cells.

10. With the aid of these organisms, it has been possible to identify bactericide, fungicide, algicide, phytotoxic and genotoxic bands.

11. Clomifene citrate at oral doses up to 2000 mg/kg/day did not induce genotoxic effects in rats

12. Since Aflatoxins are known to be genotoxic and carcinogenic, exposure through food should be kept as low as possible

13. Genotoxic: a general term encompassing all types of DNA or chromosome damage, including breaks, adducts rearrangements, mutations, chromosome aberrations, and aneuploidy.

14. Positive genotoxic effects were obtained for imatinib in an in vitro mammalian cell assay (Chinese hamster ovary) for clastogenicity (chromosome aberration) in the presence of metabolic activation

15. ParaBenzoquinone (1,4-Benzoquinone) (PBQ) is a bioactve quinone present in cigarette smoke and diesel smoke, which causes severe genotoxic effects both in vitro and in vivo

16. Rationale and Strategies for In Vitro Screening Assays Early identification of potential genotoxic issues with candidate compounds is an essential part of a product development process

17. The Scientific Committee for Food has noted that aflatoxin B1 is a potent genotoxic carcinogen and, even at extremely low levels, contributes to the risk of liver cancer.

18. Sidual Anhematopoiesis and delayed genotoxic ef fects) caused by exposure to a high challenge dose from low-LET (X-ray) or high-LET (carbon and neon ion) irradiations

19. Overall, formaldehyde is weakly genotoxic, with effects most likely to be observed in vivo in cells from tissues or organs with which the aldehyde comes into first contact.

20. Axin is a critical determinant in p53-dependent tumour suppression in which Pirh2 and Tip60 have different roles in triggering cell-cycle arrest or apoptosis depending on the severity of genotoxic stress

21. Finally, sodium orthovanadate is a potent mitigator, suppressing the acute lethality (hematopoietic syndrome) and minimizing the detrimental effects (Anhematopoiesis and delayed genotoxic effects) of radiation-induced damage to the hematopoietic system in mice

22. The Scientific Committee for Food has noted that aflatoxins, in particular Aflatoxin B#, are carcinogenic substances and even at low doses, cause cancer of the liver and in addition are genotoxic

23. Taken together, these findings indicate that vanadate would be a potent mitigator suppressing the acute lethality (hematopoietic syndrome) and minimizing the detrimental effects (Anhematopoiesis and delayed genotoxic effects) induced by TBI in mice.

24. These findings suggest that the priming low dose of low linear energy transfer (LET) X-rays induced a protective effect on the hematopoietic system, which may play an important role in both rescue from acute lethal damage (mouse killing) and prevention of late detrimental consequences (residual Anhematopoiesis and delayed genotoxic effects

25. Chrysoidine, a type of industrial Azoic dye, is a kind of illegal additive banned in China [2, 6, 7] which could cause acute and chronic toxicity to mammals administrated by oral or skin route or inhaled [8] and has been confirmed to be genotoxic, mutagenic, and carcinogenic [9-11].

26. Genotoxicity and Mutagenicity of Zeranol &Trenbolone "Genotoxic potential of xenobiotic growth promoters and their metabolites" (APMIS 109:89-95, 2001) 3. Metabolic Pathways of Estrogens as Steroidal Growth Promoting Agents "Estrogenic activity of estradiol and its metabolites in the ER-CALUX assay with human T47D breast cells" (APMIS 109: 101-107, 2001) 4.