gavage in English

noun

1

the administration of food or drugs by force, especially to an animal, typically through a tube leading down the throat to the stomach.

The test substance is usually administered orally by gavage using a stomach tube or a suitable intubation cannula.

Use "gavage" in a sentence

1. When the oral route is selected, the test chemical is usually administered by gavage; however, alternatively, test chemicals may be administered via the diet or drinking water.

2. Atrazine was administered by gavage to rats from day 22 to day 47 of age, at doses of 1-200 mg/kg body weight per day

3. When the oral route is selected, the test chemical is usually administered by gavage; however, alternatively, test chemicals may also be administered via the diet or drinking water.

4. Acrylamide induced male reproductive toxicity has been demonstrated in Long-Evans rats where given greater than or equal to 15 mg/kg/day Acrylamide orally by gavage for five consecutive days

5. 1200 mg/kg/day Benzaldehyde, and groups of 10 rats of each sex with 0, 50, 100, 200, 400 or 800 mg/kg/day Benzaldehyde, 5 days/week for 13 weeks by corn oil gavage

6. Administration of miglustat to male and female Sprague-Dawley rats by oral gavage for # years at dose levels of #, # and # mg/kg/day resulted in an increased incidence of testicular interstitial cell (Leydig cell) hyperplasia and adenomas in male rats at all dose levels

7. In a more recent carcinogenicity study (NTP, 1990) exposing B6C3F1 mice and F344/N rats to TCE by gavage, there was a significant (p < 0.05) increase in the incidences of combined hepatocellular carcinoma and adenomas (p < 0.05) in female mice (Table 3).

8. Androgenized group (GA), 12 female rats in perman-ent estrus that were treated with testosterone propi-onate and 0.5 mL of distilled water by oral gavage for six consecutive weeks; and Androgenized + met-formin group (GAmet), 12 female rats in permanent estrus that were administered testosterone propion-

9. The lowest oral lowest-observed-effect level (LOEL) was 5 mg/kg-bw per day, based upon chronic renal inflammation in male and female F344 rats in a 2-year gavage study (NTP, 1982). In the critical carcinogenicity bioassay (Maltoni et al., 1984, 1985), renal adenocarcinomas were observed at the highest concentration (100 mg/m3) only.

10. Alimentation: 1 n the act of supplying food and nourishment Synonyms: feeding Types: show 12 types hide 12 types lactation , suckling feeding an infant by giving suck at the breast infant feeding feeding an infant forced feeding , gavage feeding that consists of the delivery of a nutrient solution (as through a nasal tube) to someone who

11. An increase in the incidence of adactyly and/or shortened digits in the offspring of rats exposed to a maternally toxic dose [2000 mg/kg bw/day by gavage in corn oil] (IRDC, 1982) and embryo- or feto-toxic effects at doses less than those that were toxic to the mothers were observed in rabbits exposed to 30 and 100 mg/kg b.w.