blood-brain barrier in English

noun
1
a filtering mechanism of the capillaries that carry blood to the brain and spinal cord tissue, blocking the passage of certain substances.

Use "blood-brain barrier" in a sentence

Below are sample sentences containing the word "blood-brain barrier" from the English Dictionary. We can refer to these sentence patterns for sentences in case of finding sample sentences with the word "blood-brain barrier", or refer to the context using the word "blood-brain barrier" in the English Dictionary.

1. It's a blood-brain barrier thing.

2. The poison's broken the blood-brain barrier.

3. It does not cross the blood–brain barrier.

4. This chemical can cross the blood–brain barrier, causing permanent brain damage.

5. Artemisinin crosses the blood-brain barrier and is an inhibitor of human NOS2 (iNOS)

6. Phenylalanine uses the same active transport channel as tryptophan to cross the blood–brain barrier.

7. After it passes the blood-brain barrier, your heart rate would shoot up to 160.

8. Chlorothiazide crosses the placental but not the blood-brain barrier and is excreted in breast milk.

9. It easily crosses both the blood–brain barrier and the placenta, and is excreted into breast milk.

10. Therefore, Barbiturates have ready access to the brain because they can cross the blood brain barrier easily

11. Simvastatin is a known inhibitor of HMG-CoA reductase, and most importantly is able to cross the blood–brain barrier.

12. Astrocytes contribute to induction and maintenance of the blood–brain barrier through paracrine interactions with the pericytes and endothelial cells

13. The blood-brain barrier function was evaluated at the same time by serum albumin/CSF albumin quotient and isoelectric focusing.

14. The blood–brain barrier becomes more permeable, leading to "vasogenic" cerebral edema (swelling of the brain due to fluid leakage from blood vessels).

15. The consortium developed a novel ultrasound-based technology that delivers acoustic waves to the brain and briefly opens up the blood-brain barrier (BBB).

16. CONCLUSION: The vasogenic brain edema induced by glioma cells may not be the result of hyperpermeability of blood-brain barrier to macromolecules in plasma.

17. Blood-brain barrier: the Astrocyte end-feet encircling endothelial cells were thought to aid in the maintenance of the blood-brain barrier, but recent research indicates that they do not play a substantial role; instead it is the tight junctions and basal lamina of the cerebral endothelial cells that play the most substantial role in

18. First-generation oral Antihistamines, including diphenhydramine (Benadryl) and chlorpheniramine (Chlor-Trimeton), easily cross the blood-brain barrier and affect H1 receptors in the central nervous

19. Diphenhydramine is a first-generation ethanolamine-derivative Antihistamine, which is the scientific way of classifying Antihistamines that can cross the blood-brain barrier from those that cannot.

20. If Acetaldehyde is not detoxified, it readily crosses the blood-brain barrier and causes a type of brain stress that results in the primary symptom of brain fog

21.  Astrocytes compose and maintain the structure of the blood-brain barrier, which is a semi-permeable membrane that separates brain blood from the extracellular fluid of the spinal cord.

22. Astrocytes: Star-shaped connective tissue cells of the nervous system that link nerve cells to blood vessels and, by wrapping round brain capillaries, help to form the BLOOD-BRAIN BARRIER

23. In spite of the chemical variation, the glucuronide still possesses high affinity to opioid receptors and the polarity of the glucuronide does obviously not exclude penetration of the blood-brain barrier.

24. In Sprague-Dawley rats intravenous injection of MRP seems to alter the blood-brain barrier by release of endogenous biogenic amines associated with mast cell degranulation. This effect is not observed in Wistar rats.

25. Intranasal therapeutic agents are administered to the upper third of the nasal cavity to bypass the blood-brain barrier and access the central nervous system directly to avoid unwanted and potentially lethal side effects.

26. Astrocytes are the most numerous cell type within the central nervous system (CNS) and perform a variety of tasks, from axon guidance and synaptic support, to the control of the blood brain barrier and blood flow

27. In presence of some risk factors, such as hemolysis, sepsis, prematurity, low birth weight, it can be complicated by Bilirubinic encephalopathy (BE), when the unconjugated pigment crosses the blood-brain barrier and attaches to basal ganglia (pallidum

28. Astrocytes January 08, 2021 / Guest User star-shaped glial cells that have a number of functions, including support of the blood-brain barrier , provision of nutrients to neurons, repair to nervous tissue following injury, and facilitation of neurotransmission.

29. Anticholinergic agents are the mainstay of pharmacological treatment of OAB; however, many Anticholinergics can cross the blood-brain barrier (BBB) and may cause central nervous system (CNS) effects, including cognitive deficits, which can be especially detrimental in older patients.

30. Amines The amine is a known mediator of the blood–brain barrier (BBB) breakdown and vasogenic edema formation (Sharma et al., 1990) and capable to influence prostaglandin (PG) synthesis and its release in the CNS (Sharma and Westman, 2004).

31. Furthermore, promising results have been shown for the treatment of adenomyosis, malignant tumors of the prostate, breast and liver and for various intracranial applications, such as thermal ablation of brain tumors, functional neurosurgery and transient disruption of the blood-brain barrier.

32. The invention relates to a method for improving the bioavailability of pharmaceutical substances and for allowing said pharmaceutical substances to permeate the blood-brain barrier, said pharmaceutical substances having at least one or more amidine, guanidine, N-hydroxyamidine (amidoxime) or N-hydroxyguanidine functions.

33. Astrocytes are a principle participant in central nervous system (CNS) responses to neurological disorders or diseases [1, 2, 3].During development and homeostasis, Astrocytes coordinate immune responses by regulating microglia activation and blood-brain barrier (BBB) formation [4, 5].Through dedicated molecular cascades, Astrocytes also provide growth factors to neurons, …

34. Acetyl-L-Carnitine (ALC) is a modified amino acid that supports cellular energy production by assisting in the transport of fat into the mitochondria where it is converted into ATP (cellular fuel).* ALC is a highly bioavailable form of carnitine that can cross the blood-brain barrier, where it helps to manage typical oxidative stress, supports